Afatinib Dimaleate – 30mg
Classification: Anticancer
Afatinib Dimaleate 30mg?
It is an anticancer medicine used for lung cancer.
Uses of Afatinib Dimaleate
- • No small lung cancer
- • Advanced NSLC
- • Recurrent lung cancer
- • Mutations of the EGFR genes
Working of Afatinib Dimaleate
- • It blocks EGFR activity
- • It stops growth and multiplication of cancer cells
- • Causes starvation of cancer cells
Benefits of using Afatinib Dimaleate
- • Strong irreversible binding
- • Broad spectrum of activity
- • Slow disease progression
- • Used in failed chemotherapy
- • Better tolerated than chemotherapy
Common Side Effects
- • Diarrhea
- • Skin and nail changes
- • Mouth ulcers
- • Nausea
- • GIT upset
- • Reduced appetite
Serious Side Effects
- • Liver dysfunctions
- • Cardiovascular complications
- • Kidney dysfunctions
- • Severe dehydration
- • Lung toxicity – cough, difficulty in breathing
- • Blurred vision
Precautions
To be used cautiously in patients with –
- • Kidney dysfunctions
- • Liver dysfunctions
- • Hypertension
- • Eye issues
- • Heart disorders
- • Elderly
- • Dehydrated – electrolyte changes
- • With diuretics and an EGFR inhibitor
Contraindications
Not to be used in patients-
- • Hypersensitivity or allergy to the drug composition
- • Pregnant and breastfeeding women
Warnings
Prescription drug to be used under medical supervision.
Important Safety and Monitoring Information
- • Blood pressure
- • Liver functions
- • Kidney functions
- • Lung functions
- • Skin irritation or rashes
- • Dehydration
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