Bortezomib

Classification\- Anticancer

What is Bortezomib?

It is a targeted anticancer medicine used widely for the treatment of blood cancer and cancer of the mantle cells.

Uses of Bortezomib

Multiple Myeloma

Mantle cell lymphoma

Working of Bortezomib

It causes protein buildup in the cells, stressing the cells and inhibiting cell growth.

Common side effects

Nausea

Vomiting

Tiredness

Low blood count

Risk of infection

Serious side effects

Bone marrow suppression

Peripheral neuropathy

Severe infections

Bleeding

Anemia

Hypotension

Cardiac arrhythmias or heart failure

Respiratory distress

Liver inflammation

Renal dysfunctions

Neurological conditions - confusion, headache, seizures

Precautions:

To be used cautiously in

Liver dysfunction

Kidney disorders

Elderly patients

Heart problems

Nerve problems

Contraindications

Hypersensitivity or allergy to drug components.

Pregnant and breastfeeding women

Warnings

To be used under medical prescription.

Herpes zoster reactivation

Important Monitoring Considerations

Check for -

Liver function - elevated liver enzymes

Neurological conditions

Cardiovascular functions

Renal functions

Infections

Neuropathy assessment

Electrolytes, uric acid

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