Bortezomib

Bortezomib

Classification

\- Anticancer

What is Bortezomib?

It is a targeted anticancer medicine used widely for the treatment of blood cancer and cancer of the mantle cells.

Uses of Bortezomib

Multiple Myeloma Mantle cell lymphoma

Working of Bortezomib

It causes protein buildup in the cells, stressing the cells and inhibiting cell growth.

Common side effects

Nausea Vomiting Tiredness Low blood count Risk of infection

Serious side effects

Bone marrow suppression Peripheral neuropathy Severe infections Bleeding Anemia Hypotension Cardiac arrhythmias or heart failure Respiratory distress Liver inflammation Renal dysfunctions Neurological conditions - confusion, headache, seizures

Precautions:

To be used cautiously in Liver dysfunction Kidney disorders Elderly patients Heart problems Nerve problems

Contraindications

Hypersensitivity or allergy to drug components. Pregnant and breastfeeding women

Warnings

To be used under medical prescription. Herpes zoster reactivation

Important Monitoring Considerations

Check for - Liver function - elevated liver enzymes Neurological conditions Cardiovascular functions Renal functions Infections Neuropathy assessment Electrolytes, uric acid

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