Cabozantinib

Classification: Anticancer Medicine

What is Cabozantinib?

It is an anticancer medicine that targets kinase enzymes and inhibits cancer cell growth and angiogenesis.

Uses of Cabozantinib –

  • • Kidney cancer
  • • Liver cancer
  • • Thyroid cancer

Working of Cabozantinib

  • • Blocks tumor growth
  • • Starvation of cancer cells
  • • Inhibit metastasis

Common side effects

  • • Tiredness
  • • Diarrhea
  • • Mouth ulcers
  • • Weight loss
  • • High blood pressure
  • • Hair and skin changes
  • • Skin rashes, swelling, and redness
  • • Constipation
  • • High blood pressure
  • • Stomach pain

Serious side effects

  • • Gastrointestinal bleeding
  • • Thromboembolic events
  • • Delayed wound healing
  • • Liver toxicity
  • • Cardiac dysfunctions
  • • Dehydration
  • • Proteinuria
  • • Severe hypertension
  • • Damage in the bone of the jaw

Precautions:

To be used cautiously in-

  • • Liver impairment
  • • Heart problems
  • • Kidney dysfunctions
  • • Bleeding disorders and blood clots
  • • Children
  • • Concomitant use with anticoagulants or antiplatelet

Contraindications

  • • Hypersensitivity or allergy to drug components.
  • • Pregnant and breastfeeding women

Warnings

To be used under medical prescription.

Important Monitoring Considerations

  • • Monitor-
  • • Liver functions
  • • Kidney functions
  • • Cardiac functions
  • • Access bleeding risks
  • • Blood pressure
  • • ECG
  • • Access wound healing

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