Calcium Leucovorin 15mg
Classification: Folic acid Derivative
What is calcium leucovorin injection?
It is used as an adjuvant cancer care treatment to –
- Reduce the toxicity
- Side effects of chemotherapy
- Enhance chemotherapy efficacy
Uses of leucovorin
- Colorectal cancer (adjuvant to 5-fluorouracil)
- Rescue therapy after methotrexate, trimethoprim and methotrexate therapy
- Adjuvant to anti-folate agents in blood cancer, lymphomas, solid tumors, etc.
How does it work?
- Recovering folate levels in anti-folate cancer therapies
- Enhanced the chemotherapy effects
Common side effects
- Nausea
- Tiredness
- Skin rashes/mouth sores
- GIT upset
Serious side effects
- Neurological conditions – seizures
- Anaphylactic reaction – swelling of lips, face, tongue etc.
- Severe gastrointestinal side effects
Contraindications
- Not to be used if any previous allergy or hypersensitivity to leucovorin or any excipients
- Low RBC count
- Breastfeeding mothers
- Pregnant women
Warnings
To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.
Not to be used as a folate supplement.
Important safety and monitoring information
- Regularly monitor blood count
- Hepatic and neurological assessments
- Manage infection risks
- Assess ocular and renal functions
Storage
To be stored in the refrigerator-
At 2–8 degrees Celsius.
Protected from light.
Administration Instructions
- To be administered IV and IM
- To be used immediately after reconstitution
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