Daunorubicin

Classification - Anticancer Medicine

Daunorubicin?

It is an anticancer medicine used for leukemia (blood cancers).

Uses of Daunorubicin

Acute leukemia (AML, ALL)

How does Daunorubicin work?

Daunorubicin inhibits DNA replication and division.

Oxidizes the cell membrane, causing cell death.

Common side effects

Low blood count

Hair loss

Mouth ulcers

Reddish colored urine

Weakness

High temperature

Loss of appetite

Serious side effects

Myleosuppresion

GIT bleeding

Hemorrhage

Cardio toxicity - irregular heartbeats, shortness of breath

Fluid retention

Liver toxicity

Painful urination

Precautions

It should be used carefully in -

Heart problems

Kidney diseases

Gout

Kidney stones

Liver diseases

Previous viral infection- chicken pox, shingles

Contraindications

Allergy to drug components

Breastfeeding mothers

Pregnant women

Warning

To be used under medical prescription only.

Safety and monitoring information

Monitor regularly-

Total blood count

Cardiac functions

Slow infusion to prevent tissue necrosis

Use effective contraception during treatment

Administration Instructions

For intravenous administration only, as a slow IV infusion.

To be used immediately after reconstitution.

Storage

Store at 2-8 degrees Celsius, protected from light.

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