Daunorubicin IP 20 mg

Classification: Anticancer Medicine

Daunorubicin?

It is an anticancer medicine used for leukemia (blood cancers).

Uses of Daunorubicin

  • • Acute Myeloid Leukemia (AML)
  • • Acute Lymphoblastic Leukemia (ALL)

How Does Daunorubicin Work?

Daunorubicin inhibits DNA replication and division.
Oxidizes the cell membrane, causing cell death.

Common Side Effects

  • • Low blood count
  • • Hair loss
  • • Mouth ulcers
  • • Reddish colored urine
  • • Weakness
  • • Fever
  • • Loss of appetite

Serious Side Effects

  • • Myelosuppression
  • • GIT bleeding
  • • Hemorrhage
  • • Cardiotoxicity – irregular heartbeats, shortness of breath
  • • Fluid retention
  • • Liver toxicity
  • • Painful urination

Precautions

It should be used carefully in:

  • • Heart conditions
  • • Kidney disease
  • • Gout
  • • Kidney stones
  • • Liver disorders
  • • Previous viral infection: chickenpox, shingles

Contraindications

  • • Allergy to drug components
  • • Breastfeeding mothers
  • • Pregnant women

Warnings

To be used under medical prescription only.

Safety and monitoring information

Monitor regularly-

  • • Total blood count
  • • Cardiac functions
  • • Slow infusion to prevent tissue necrosis
  • • Use effective contraception during treatment

Administration Instructions

For intravenous administration only, as a slow IV infusion. To be used immediately after reconstitution.

Storage

Store at 2-8 degrees Celsius, protected from light.

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