Docetaxel (20mg)

Classification: Oncology Medicine

Docetaxel?

It is an anticancer medicine that is used against various cancers and solid tumors.

Uses of Docetaxel

  • • Solid tumors
  • • Breast Cancer
  • • Lung cancer (Non-small cell)
  • • Stomach cancer
  • • Pancreatic cancer
  • • Cancer of the head and neck

How does Docetaxel work?

It inhibits cancer cell growth and multiplication

Causes cancer cell death.

Common side effects

  • • Alopecia
  • • Nausea
  • • Vomiting
  • • Fluid retention and swelling in the body
  • • Muscle pain and joint pain
  • • Taste changes
  • • Nail discoloration

Serious side effects

  • • Peripheral neuropathy
  • • Neutropenia
  • • Severe fluid retention
  • • Bleeding
  • • Heart complications
  • • Liver dysfunctions

Precautions

To be used carefully in:

  • • Low blood count
  • • Immune-compromised patients
  • • Cardiac issues
  • • Elderly patients
  • • Liver dysfunctions

Contraindications

  • • Not to be used if any previous allergy or hypersensitivity to docetaxel or any excipients.
  • • Breastfeeding mothers
  • • Pregnant women

Important Monitoring Considerations

  • • Blood count
  • • Kidney functions
  • • Liver functions
  • • Peripheral neuropathy

Important Handling Instructions

  • • Docetaxel should be handled while wearing gloves to minimize dermal exposure due to its cytotoxic properties.
  • • Docetaxel gets precipitated by Needles or intravenous sets made of aluminum, causing a loss of potency.

Storage

Store at 2-8 degrees Celsius, protect from light.

Administration Instructions

To be administered Intravenously, IM, subcutaneously, or Intrathecal.

It is vesicant, can cause tissue or muscle damage.

Warnings

To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.

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