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Active Chemical Molecule

Domperidone + Esomeprazole

Therapeutic Class: Acid Reflux Medicine

Classification: Acid reflux medicine

What is Esomeprazole ER & Domperidone SR?

It is a combination of 2 medicines.

Esomeprazole is added as an extended-release dose.

Domperidone is added in sustained-release form.

Esomeprazole ER & Domperidone SR uses

It is widely used in –

  • Gastric acid reflux
  • GERD
  • Indigestion
  • Bloating
  • Heartburn
  • Nausea and vomiting

Esomeprazole ER & Domperidone SR side effects

  • Dry mouth
  • Headache
  • Diarrhea /constipation
  • Stomach pain
  • Dizziness
  • Drowsiness

Serious side effects

  • Irregular heartbeat
  • Severe diarrhea
  • Allergic reaction
  • Muscle tremors
  • Muscle twitches

Long-term risks/side effects

Using it for a long duration leads to –

  • Hypomagnesaemia
  • Bone fractures
  • Stomach infections
  • Vitamin B12 deficiency

Precautions to be maintained with Esomeprazole ER & Domperidone SR capsule

The long-term use of esomeprazole /domperidone reduce gut absorption.

It leads to magnesium /calcium deficiency.

Do not drive, since it causes sleepiness.

Drinking alcohol worsens stomach acid.

What are Esomeprazole ER & Domperidone SR warnings?

Do not use it in conditions of –

  • Severe organ failure
  • Active stomach ulcers
  • Mechanical blockage
  • Electrolyte imbalance
  • Pituitary tumor

The functions to be monitored for

  • Heart functions
  • Liver /kidney functions
  • Electrolyte balance
  • Vitamin B-12 levels
  • Bone mineral density
  • Prolactin levels

Drugs to be avoided with Esomeprazole ER & Domperidone SR

The PPIs reduce drug absorption and block metabolic enzymes.

Certain combinations may lead to –

  • Reduced efficacy: Esomeprazole reduces drug absorption. Avoid its use with Clopidogrel, Antifungals, Antivirals, and Heart failure medications.
  • Increased toxicity: Esomeprazole reduces drug clearance; it slows down drug metabolism. Avoid with Anti-seizure medicines, Immunosuppressants, and Warfarin.
  • Cardiac toxicity: Domperidone leads to QT prolongation. It must be strictly avoided with cardio-toxic drugs such as HIV medicines and Antipsychotics.
  • GIT side effects: Increased risk with anticholinergic and opioid drugs.

Gandhi Medicos – The Leading Drug Distributor

Gandhi Medicos is a drug supplier with global reach.

We outsource drugs from the top brands and generic drug manufacturers.

We offer global shipments. Our products are verified and trusted for their authenticity.

We have the strongest distribution network.

Our portfolio expands to –

  • Life-saving drugs
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Frequently Asked Questions about Domperidone + Esomeprazole

Use it at a gap of 2 hours from meals. Food interferes with its absorption.

Referral & Authority Resources for Domperidone + Esomeprazole

Refferal Link:https://www.ncbi.nlm.nih.gov/books/NBK547892/
Refferal Link:https://pubmed.ncbi.nlm.nih.gov/42271600/

Formulations based on "Domperidone + Esomeprazole" (1)

Eprakast DSR
GastroenterologyVerified Supply

Eprakast DSR

Esomeprazole ER & Domperidone SR Capsules

Product Name Eprakast DSR  Composition Esomeprazole ER & Domperidone SR Capsules Form Capsule Manufactured By Aprazer Healthcare Prescription Required Storage Store below 30°C

Specialty BrandAprazer Healthcare
Unit DosageCapsule ()
Clinical SourceAprazer Healthcare
Temp Tracked: Store below 30°C
Inspect

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