Doxorubicin Hydrochloride 10 mg
Classification: Anticancer Medicines
Doxorubicin?
Doxorubicin is an anticancer medicine that kills viable cancer cells for various types of cancer.
Uses of Doxorubicin
- • Blood cancers
- • Leukemia
- • Lymphocytic cancers
- • Breast cancer
- • Lung cancer
- • Sarcomas
- • Ovarian cancers
Working of Doxorubicin
- • Blocks the enzyme topoisomerase 2
- • Inhibits cancer cell division and growth
- • Causes cancer cell death
Common Side Effects of Doxorubicin
- • GIT upset – Nausea, vomiting
- • Mouth and throat ulcers
- • Hair loss
- • Urine discoloration
- • Red eyes
Serious Side Effects
- • Difficulty in breathing
- • Skin rash
- • Seizures
- • Red blood in stool and vomit
Toxicities
Doxorubicin causes dose-dependent toxicities:
- • Cardiac toxicity
- • Myelosuppression
- • Severe local tissue necrosis
Contraindications
- • Allergy to the drug components
- • Breastfeeding mothers
- • Pregnant women
Precautions
To be used cautiously in patients with:
- • Heart disease
- • Low blood count
- • Liver disease
Warnings
To be used under doctor’s prescription as a slow intravenous infusion.
Important Safety and Monitoring Considerations
Regularly monitor:
- • Liver function
- • Cardiac function
- • Total blood count
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