Everolimus

Everolimus (5mg)

Classification: Anticancer and Organ Transplant medicine

Everolimus?

It has anticancer and immunosuppressive properties. It is widely used for both cancer treatment and to prevent organ rejection.

Uses of Everolimus-

Anticancer uses-

Breast cancer

Kidney cancer

Pancreatic cancer

Prevention of Organ Transplant -

Kidney transplant

Liver transplant

Working of Everolimus

Inhibit the signals that cause cells to grow and respond, thus inhibiting immune response and cancer cell growth.

Common side effects

Nausea

Vomiting

Mouth ulcers

Risk of infections

High blood sugar

High cholesterol

Tiredness

Skin rashes

Serious side effects

Mylosuppression

Gastrointestinal bleeding

Lung toxicity

Kidney toxicity

Delayed wound healing

Precautions using Everolimus

To be cautiously used in -

Lung disorders

Liver impairment

Immune compromised

Before or after surgery

Bleeding disorders

High cholesterol and blood glucose levels

Drug interactions with drugs that affect the CYP3A4 enzyme- ketoconazole, phenytoin.

Contraindications

Not to be used in patients-

Hypersensitivity or allergy to the drug components.

Pregnant and breastfeeding women

Should avoid grapefruit juice

Warnings

Prescription drug to be used under medical supervision.

Important safety and monitoring information

Liver functions

Kidney functions

Total blood count

Lipid profile

Glucose levels

Respiratory function

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