Everolimus 5mg

Classification: Anticancer and Organ Transplant Medicine

What is Everolimus?

Everolimus has anticancer and immunosuppressive properties. It is widely used for both cancer treatment and to prevent organ rejection.

Uses of Everolimus

  • • Anticancer uses – Breast cancer, Kidney cancer, Pancreatic cancer
  • • Prevention of Organ Transplant – Kidney transplant, Liver transplant

Working of Everolimus

It inhibits the signals that cause cells to grow and respond, thus reducing immune response and cancer cell growth.

Common Side Effects

  • • Nausea
  • • Vomiting
  • • Mouth ulcers
  • • Risk of infections
  • • High blood sugar
  • • High cholesterol
  • • Tiredness
  • • Skin rashes

Serious Side Effects

  • • Myelosuppression
  • • Gastrointestinal bleeding
  • • Lung toxicity
  • • Kidney toxicity
  • • Delayed wound healing

Precautions using Everolimus

To be cautiously used in :

  • • Lung disorders
  • • Liver impairment
  • • Immune-compromised conditions
  • • Before or after surgery
  • • Bleeding disorders
  • • High cholesterol and blood glucose levels
  • • Drug interactions (CYP3A4 inhibitors: ketoconazole, phenytoin)

Contraindications

Not to be used in patients-

  • • Hypersensitivity or allergy to the drug components.
  • • Pregnant and breastfeeding women
  • • Should avoid grapefruit juice

Warnings

Prescription drug to be used under medical supervision.

Important Safety and Monitoring Information

  • • Liver functions
  • • Kidney functions
  • • Total blood count
  • • Lipid profile
  • • Glucose levels
  • • Respiratory function

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