Ivermectin

Classification – Parasite Infection Medicine

Ivermectin?

It is a medicine used to kill parasites or worms and is widely used in parasitic infections. It is WHO’s recommended essential medicine.

Uses of Ivermectin

Used against parasitic infections:

  • • Filarial worms
  • • River blindness
  • • Scabies
  • • Head lice
  • • Hook-worm infection

Working of Ivermectin

  • • It causes paralysis of the parasite
  • • Kills parasites

Benefits

  • • It has a broad spectrum of activity, used against many parasites
  • • Useful in community treatment initiatives
  • • Well tolerated
  • • Repeated doses are safe

Common Side Effects

  • • Headache
  • • Dizziness
  • • Muscle pain
  • • Diarrhea
  • • Skin rashes
  • • Fever

Serious Side Effects

  • • Peeling of the skin
  • • Severely low blood pressure
  • • Seizures
  • • Mental confusion
  • • Inflammation in the brain

Precautions

To be cautiously used in –

  • • Psychiatric disorders – seizures, depression
  • • Severe liver disorder
  • • Pregnant and breastfeeding women
  • • High parasitic burden
  • • Elderly patients
  • • With CNS depressant drugs

Contraindications

  • • Allergy to Ivermectin
  • • Meningitis
  • • 1st trimester of pregnancy
  • • Severe liver impairment
  • • Children weighing less than 15kg or under 5 years of age
  • • Concomitant infections

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