Lapatinib Ditosylate IP -250mg
Classification – Anticancer Medicine
What is Lapatinib Ditosylate?
Lapatinib is an anticancer medicine that is used orally against solid tumors and breast cancers.
Uses of Lapatinib Ditosylate
- • Advanced-stage Breast cancer
- • Metastatic Breast Cancer
- • Lung cancer
Working of Lapatinib Ditosylate
It causes cancer cell death by inhibiting growth receptors.
It inhibits signals for cancer cell growth and division.
Adverse side effects
- • Anorexia
- • Diarrhea
- • Dermatological side effects
- • Stomatitis, constipation, and abdominal pain
- • Palmar-plantar erythrodysaesthesia
- • Pain in the extremity, back pain
- • Alopecia
Severe side-effects
- • Bleeding
- • Dehydration
- • QT prolongation
- • Hand and foot syndrome
- • Toxicities
- • Cardiac toxicities
- • Hepatotoxicity
- • Interstitial Lung Disease
- • Pneumonitis
- • Mineral imbalance
Contraindications
Not to be used in patients –
- • Allergy to the drug components
- • Breastfeeding mothers
- • Pregnant women
Precautions
To be used cautiously in patients with
- • Heart disease
- • Liver disease
- • Blood disorders
Warnings
- • To be used under medical supervision
Important Safety and Monitoring Information
Regularly Monitor –
- • The liver function
- • Cardiac function
- • Electrolyte balance
- • Hydration status
- • Blood count
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