Maraviroc

Maraviroc

Classification: HIV-1 medicine

What is Maraviroc?

It is an anti-retroviral medicine used for HIV-1 infection.

Uses of Maraviroc

• • HIV-1 infections
• • Resistant or intolerant to other anti-retrovirals.
• • CCR5 tropic HIV-1 infection

How does Maraviroc work?

It inhibits the binding of the virus to the receptor. Downregulating its action.

Common Side Effects

• • Cough
• • Fever
• • Flue
• • Dizziness
• • Muscle pain
• • Joint pain
• • Fatigue
• • GIT upset

Serious Side Effects

• • Severe liver toxicity
• • High risk of infections
• • Low blood pressure
• • Irregular heartbeat
• • Coordination issues
• • Mood changes

Precautions of Maraviroc

To be used cautiously in patients with –

• • Liver disorders
• • Heart disorders
• • Kidney dysfunctions
• • Low blood pressure
• • Weak immunity

Contraindications

• • Allergy to the drug
• • Breastfeeding mothers
• • Pregnant women

Warning

• • To be used under medical prescription only
• • It can’t be used as a single treatment for HIV-1.
• • Effective against CCR5-tropic HIV-1 infection only.

Important Monitoring Considerations

Monitor-

• • Liver functions
• • Low blood pressure
• • Increased risk of infections
• • Skin rashes
• • Fever
• • Viral count
• • CD4+ count

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