Maraviroc

Maraviroc

Classification -

HIV-1 medicine

What is Maraviroc?

It is an anti-retroviral medicine used for HIV-1 infection.

Uses of Maraviroc

HIV-1 infections Resistant or intolerant to other anti-retrovirals. CCR5 tropic HIV-1 infection

How does Maraviroc work?

It inhibits the binding of the virus to the receptor. Downregulating its action.

Common side effects

Cough Fever Flue Dizziness Muscle pain Joint pain Fatigue GIT upset

Serious side effects

Severe liver toxicity High risk of infections Low blood pressure Irregular heartbeat Coordination issues Mood changes

Precautions of Maraviroc

To be used cautiously in patients with - Liver disorders Heart disorders Kidney dysfunctions Low blood pressure Weak immunity

Contraindications

Allergy to the drug Breastfeeding mothers Pregnant women

Warning

To be used under medical prescription only It can't be used as a single treatment for HIV-1. Effective against CCR5-tropic HIV-1 infection only.

Important Monitoring Considerations

Monitor-

Liver functions Low blood pressure Increased risk of infections Skin rashes Fever Viral count CD4+ count

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