Maraviroc

Classification - HIV-1 medicine

What is Maraviroc?

It is an anti-retroviral medicine used for HIV-1 infection.

Uses of Maraviroc

HIV-1 infections

Resistant or intolerant to other anti-retrovirals.

CCR5 tropic HIV-1 infection

How does Maraviroc work?

It inhibits the binding of the virus to the receptor. Downregulating its action.

Common side effects

Cough

Fever

Flue

Dizziness

Muscle pain

Joint pain

Fatigue

GIT upset

Serious side effects

Severe liver toxicity

High risk of infections

Low blood pressure

Irregular heartbeat

Coordination issues

Mood changes

Precautions of Maraviroc

To be used cautiously in patients with -

Liver disorders

Heart disorders

Kidney dysfunctions

Low blood pressure

Weak immunity

Contraindications

Allergy to the drug

Breastfeeding mothers

Pregnant women

Warning

To be used under medical prescription only

It can't be used as a single treatment for HIV-1.

Effective against CCR5-tropic HIV-1 infection only.

Important Monitoring Considerations

Monitor-

Liver functions

Low blood pressure

Increased risk of infections

Skin rashes

Fever

Viral count

CD4+ count

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