Ribociclib

Classification- Anticancer Medicines

What is Ribociclib?

It is an anticancer Medicine used against hormone-positive advanced-stage breast cancer.

Uses of Ribociclib

Hormone receptor-positive breast cancer

HER-2 negative cancer

How does Ribociclib work?

Blocks cancer cell proteins

Inhibits cancer cell division and multiplication

Ribociclib Benefits

Increase progression-free survival

Enhance the effect of endocrine therapy

Suitable for both young and elderly women

Common side effects

Nausea

Vomiting

Headache

Rashes on the skin

Loss of hunger /appetite

Diarrhea

Hair loss

Back pain

Tiredness

Sore throat

Cough

Serious side effects of Ribociclib

Low blood count

QT prolongation

Severe liver dysfunction

Severe infection

Precautions while using Ribociclib

To be cautiously used in patients with -

Heart disorders

Liver dysfunctions

Bleeding disorders

Alcohol abuse

Concomitant use with other drugs

Contraindications

Allergy or hypersensitivity to any drug component.

Breastfeeding mothers

Pregnant women

Severe hepatic disease

Warning

Take when recommended by the doctor.

Maintain contraception during the treatment.

Important Safety and Monitoring Information

Blood count

Liver functions

Cardiac functions

Electrolyte levels

Drug interactions -

Antivirals-Ritonavir, Lopinavir

Antifungals-Ketoconazole, Fluconazole

Anticonvulsants- Phenytoin, barbiturates

Cardiac drug - Amiodarone, Diltiazem

Immunosuppressant -cyclosporine

Proton pump inhibitors - Omeprazole, Esomeprazole

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