Sofosbuvir
Classification – Hepatitis C Medicine
What is Sofosbuvir?
An antiviral against HCV, used in combination for the treatment of Chronic Hepatitis C.
Uses of Sofosbuvir
- • Chronic Hepatitis C
- • HCV-HIV co-infections
Working of Sofosbuvir
It inhibits viral DNA synthesis and is a prodrug that is activated in the liver.
Benefits
- • Can be used in cirrhosis (both compensated and decompensated)
- • Can be used in HIV co-infections
- • In children > 3 years
- • Post liver transplant
- • Low resistance risk
Common Side Effects
- • Nausea
- • Dizziness
- • Headache
- • Digestive issues
- • Tiredness
- • Diarrhea
Serious Side Effects
- • Severe Bradycardia (when taken with amiodarone)
- • Causes Hepatitis B reactivation
- • Severe liver failure
- • Severe anemia upon use with ribavirin
- • Depression, mood swings, and confusion
Precautions
To be used cautiously in patients
- • Kidney disorders
- • Liver disorder
- • Hepatitis B co-infections – cause reactivation
- • HIV co-infection
- • When used in combination with ribavirin and amiodarone
Contraindications
- • Allergy or hypersensitivity to drug components
- • Breastfeeding mothers
- • Pregnant women
Warning
It is a prescription drug to be taken under medical supervision only.
Important Safety and Monitoring Information
- • Regular monitoring of hepatic functions
- • Renal functions
- • Cardiac functions
- • Co-infections
- • Neuropsychiatric adverse reactions
- • Drug interactions – Ribavirin and Amiodarone
- • Not to be used alone for HCV infections
Gandhi Medicos – Trusted Hepatitis C Medicines
Gandhi Medicos offers an affordable range of Hepatitis C medicines. The super–specialty pharmacy, trusted by the leading doctors, physicians, and the hospital.
âś… Why Choose Gandhi Medicos?
- • Trusted by 25,000+ satisfied clients globally
- • Preferred by doctors, hospitals, and transplant specialists
- • Delivering to over 50+ countries
- • 100% Authentic, Verified Medicines – WHO-GMP-certified
- • Expertise in Chronic & Critical Care – including HIV, Hepatitis, and Transplant Therapy
đź’Ľ What Sets Us Apart?
- • Reliable distribution of branded & generic immunosuppressants
- • Temperature-controlled shipping for medicine safety
- • Responsive customer support
- • Strong partnerships with leading pharmaceutical manufacturers
