Zolderonic acid IP- 4mg
Composition: Zolderonic acid IP- 4mg
Classification: Cancer Support Medicine
What is Zolderonic?
Cancer treatment often causes bone loss, and it is widely used to treat cancer-related bone complications and osteoporosis.
Uses of Zolderonic
- • Osteoporosis
- • High calcium levels caused by malignancies
- • Secondary cancers in the bone
- • Chronic bone disorder
- • Bone marrow cancers
- • Bone lesions
How does Zolderonic work?
Osteoclast causes bone dissolution.
Inhibiting osteoclasts stops bone dissolution, preventing bone integrity.
Common side effects
- • Diarrhea
- • Loss of appetite
- • Bone, muscle pain
- • Nausea
- • Vomiting
- • Fluid retention
- • Dizziness
- • Dryness of the skin
Serious side effects
- • Lowered calcium levels – tingling in fingers
- • Kidney failure
- • Irregular heartbeat
- • Bone fractures
- • Osteonecrosis of the jawbone
- • Eye inflammation
- • Blood in urine
- • Dizziness, confusion
- • Shortness of breath
- • Rapid weight gain
- • Decreased vision
Precautions
To be used cautiously in:
- • Kidney disorders
- • Any dental procedures
- • Respiratory disorder
- • Elderly
- • Thyroid disorder
- • Cardiovascular disease
- • Vitamin D levels or low calcium levels
Contraindications
- • Not to be used if any previous allergy or hypersensitivity to Zolderonic acid or any excipients.
- • Breastfeeding mothers
- • Pregnant women
Warnings
To be used under stringent monitoring conditions and a doctor’s prescription.
Important safety and monitoring information
Regular monitor –
- • Kidney functions
- • Liver functions
- • Cardiac functions
- • Renal functions
- • Respiratory functions
Administration Instructions
- • Administer as a slow IV infusion
- • Do not give as an IV push/bolus
- • To be used immediately after reconstitution
- • Ensure patient hydration before infusion
- • Do not mix with calcium-containing IV solutions
Storage
It should be stored at 2-8 degrees Celsius, protected from light.
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