Ledifos Tablet: A combination medicine for Hepatitis C

Ledifos Tablet 90 mg/400 mg (Ledipasvir/sofosbuvir)

Hepatitis C is an infection caused by a virus that stimulates liver inflammation that periodically may lead to severe liver damage. The HCV (Hepatitis C) is a blood-borne virus that spreads via infected or contaminated blood, such as from sharing syringes or unsterile tattoo devices. The hepatitis virus can result in both acute and chronic hepatitis varying in stringency from a mild ailment to a severe.

Until previously, hepatitis C therapy needed oral medications and weekly injections that many HCV-infected patients couldn’t take due to other health issues or unwanted side effects. But now that’s changing. Currently, chronic Hepatitis C is generally curable with only oral medications that need to be taken every day for about two to six months, depending upon the patient’s condition and prescription of the doctor. Antiviral drugs such as ledifos tablets can cure Hepatitis C of chronic type.

Ledifos Tablet

The ledifos tab is a combination of the two antiviral medicines. Ledifos tablet is a fixed-dose combination of Ledipasvir and sofosbuvir. The healing rate of Hepatitis infected patients with genotype 1 is 94-99%.

Ledipasvir/sofosbuvir is a two-drug combination used to treat Hepatitis C. It is an oral dosage form administered as a single pill regularly comprising 90 mg of ledipasvir, a viral NS5A inhibitor, and 400 mg of sofosbuvir, a nucleotide inhibitor of the viral RNA polymerase. Ledipasvir is generally used in a mixture with sofosbuvir for patients infected with chronic hepatitis C of genotype 1, and this drug has shown efficacy. Sofosbuvir is also utilized to treat hepatitis C of genotypes 1,2,3 and 4 in combination with the pegylated interferon and ribavirin or with ribavirin alone. Sofosbuvir is used in hepatitis C infected patients with an HIV coinfection.

The ledifos price in India is almost Rs. 13,000/strip and Rs. 3000-6500/ bottle.

Usage and Dosage of Ledifos Tablets

Ledifos tab 90mg/400mg should be consumed in the prescribed dose and extent as suggested by the doctor. It should be taken at the same time regularly. It can be taken with or without food as per the patient’s wish, or sometimes the doctor may suggest according to the patient’s condition. It is strictly advised not to consume more than the prescribed dose without consulting a doctor or pharmacist.

Inform your doctor everything about the health condition such as kidney or liver disorders so as per the requirement regular dose can be prescribed.

Side Effects of Ledifos Tablet

The common side effects of ledifos are headaches and tiredness. The patient should drink a sufficient amount of fluid and consume a healthier diet to overcome or avoid the side effects of the drug. Before taking medicine, you should inform your doctor whether you are regularly consuming any other supplement or medicine. Most side effects do not need any medical attention and fade away as the body adapts to the medicine.

Some of the major and minor side effects of ledifos are as follows-

• Nausea
• Diarrhea
• Irritability
• Loss of appetite
• Chest pain (rare)
• Muscle cramps and pain
• Vomiting
• Insomnia
• Abdominal pain (rare)

Precautions while using Ledifos Tablets

• Unless and until necessary, this medicine is not recommended for pregnant women and breastfeeding women.
• This medication should be taken with severe caution if the patient has a history of Hepatitis B. The drug may increase the threat of reactivation of that infection of hepatitis B.
• This medicine is not used for children below 12 years of age.
• Patients having kidney diseases may experience adverse effects due to this drug.

Lastly, do not consume any drug on your own without proper consultation with your doctor or a pharmacist.