Obesity is often underestimated, merely linked to body weight or metabolic conditions like diabetes, heart complications. But it extends beyond, it is linked to an increased cancer risk.

What is Obesity?

It is the excessive fat that exceeds the normal body mass index (30 or above). It occurs due to several factors – poor diet, loss of physical activity, and stress.

Health risk due to obesity?

Obesity is a gateway to serious health complications –

• • Diabetes – type 2
• • Heart diseases
• • Osteoarthritis
• • Nephrology diseases
• • Hypertension
• • Liver diseases—fatty liver
• • Respiratory diseases
• • Cancer

Various Cancers Linked to Obesity

Obesity increases the risk of developing certain types of cancers—

• • Kidney cancer
• • Liver cancer
• • Pancreatic cancer
• • Colon cancer
• • Rectum cancer
• • Prostate cancer
• • Breast cancer
• • Uterine cancer

The link between obesity and cancer

• • Chronic inflammation – The long-term inflammation due to excessive fat damages DNA, causing mutations and cancer.
• • Reduces immune functions – obesity inhibits the T cell activity of the immune cells, significantly increasing the risk of chronic infections and mutagens.
• • Altered metabolism – Increased glucose levels and acidic environment in the body create a favorable environment for cancer growth and proliferation.
• • Oxidative stress – the increase in oxidative stress on cells causes the generation of free radicals, which can mutate the DNA of the cells.
• • Hormonal imbalances – The fluctuation in endocrine hormones causes overexpression of hormone receptors.

Visceral fat – the hidden danger

The fat of the internal organs poses a significant risk, as fat cells (adipocytes) produce adipokines that directly promote cancer cell growth and proliferation. These signals also fuel inflammation and other hormonal imbalances.

Lowering weight lowers the risk of cancer

Lowering a nominal weight exponentially lowers the risk of cancer –

• • Reduces inflammation
• • Balances hormones
• • Regulate sugar levels
• • Improves immune sensitivity

Preventive measures to reduce obesity

• • Healthy eating
• • Regular exercise
• • Limiting alcohol and tobacco
• • Regular health screenings

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