Apraketo- 200 mg

Composition: Ketoconazole 200mg

Therapeutic class: Antifungal

What is Apraketo- 200?

It is an antifungal medicine used to treat fungal or yeast infections.

Uses of Apraketo-200

It is for severe systemic fungal infections

How does Apraketo work?

Ketoconazole works by -

Blocking ergosterol synthesis
Which breaks the fungal cell membrane integrity
Causes fungal cell death.

Common Side-effects

Skin rashes
Irregular heartbeats
Abdominal pain
Loss of appetite
Dark urine
Fatigue
Diarrhea

Serious Side Effects

These are dose-dependent side effects that occur at high doses or long-term use
Severe liver toxicity –jaundice, pale urine, and stool
Adrenal insufficiency
Arrhythmia
QT prolongation

Contraindications

Not to be used in patients –

Hypersensitive or allergic to the drug or its excipients.
Breastfeeding mothers
Pregnant women

Precautions

It should be used cautiously in patients with

Adrenal problems
Alcohol abuse
History of irregular heartbeat
Liver disease
Hypoachlorhyrda

Warning

To be used under medical prescription only

Important Safety and Monitoring Information

Regular monitoring of the liver function, cardiac rhythms, and adrenal functions.

General Instructions

Do not skip doses
Take after food, at the same time

Drug Interactions

Ketoconazole should be used with extreme caution with

Anti-cholesterol drugs, anticoagulants, cardiovascular drugs, immunosuppressants, HIV, or antipsychotics.

Apraketo- 200mg