Ketoconazole

Ketoconazole 200 Mg

Classification

-Antifungal Medicine

Ketoconazole- 200 mg?

It is used for various systemic fungal infections and yeast infections.

Uses -

Systemic fungal infections Mucocutaneous candidiasis Tinea infections Dermatitis Deep-seated fungal infections Psoriasis, caused by a fungal infection

Working of Ketoconazole -

Breaks the fungal cell membrane integrity. Causes fungal cell death.

Common Side Effects -

Nausea Vomiting Diarrhea Fatigue Stomach ache

Severe Side Effects -

Painful skin rashes Menstrual irregularities Gynecomastia Sexual dysfunction Arrhythmia Suppression of the adrenal glands Liver dysfunction Jaundice Electrolyte imbalance

Toxicities:

Liver toxicity Adrenal insufficiency Arrhythmia QT prolongation

Precautions:

To be used cautiously in patients with Any heart problem Liver disorders Alcohol abuse Achlorhydra

Contraindications

Not to be used in patients - Hypersensitive or allergic to the drug composition. Breastfeeding mothers Pregnant women

Warning

To be used under medical prescription only

Important Safety and Monitoring Information

Regularly monitor- Liver function Heart rhythms and Hormonal functions

Drug interactions

Ketoconazole should be used with extreme caution with Cholesterol medicines- statins, fibrates Anticoagulants- Warfarin, Heparins Cardiovascular drugs-beta blockers ,calcium channel blocker Antihypertensive- diuretics , ACE ace inhibitors Immunosuppressant- corticosteroids HIV- DDA Antipsychotics- antidepressants

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