Dacikast -

Composition: Daclatasvir 60mg

Classification: Hepatitis C medicine

What is Dacikast?

It is a hepatitis C medicine, often used in combination with other drugs for HCV infections.

Uses of Dacikast

Chronic Hepatitis C

Against HCV strains -1-3 and others

How does Dacikast work?

NA5A protein inhibition

It inhibits viral replication, assembly, and release

Block new viral cell formation

Benefits -

Rapidly reduces viral load

Well tolerated, fewer side effects

Shorter treatment duration

Broad spectrum of activity (genotypes 1-3)

Safe in HIV co-infections

Can be used in compensated cirrhosis

Can be used post-liver transplant

Less risk of the development of resistance

Common Side Effects

Nausea,

Dizziness,

Headache,

Digestive issues,

Tiredness,

Diarrhea

Severe Side Effects

Severe fall in RBC count when used with Ribavirin

Anxiety, confusion

Elevated liver enzymes,

Hepatic decompensation in advanced-stage liver disorder

Low heart rate when used with Amiodarone

Precautions

To be used cautiously in patients -

Heart disorder

Decompensated liver cirrhosis

HIV co-infections

Drug interactions

Contraindications

Not to be used in drug allergy

Breastfeeding mothers

Pregnant women

Warning

Use when prescribed by doctor.

Not to be used as monotherapy for HCV infections.

Important Safety and Monitoring Information

Regular monitoring of hepatic functions, renal functions, cardiac functions, co-infections,

Drug interactions -

Ribavarin and Amiodarone

Dacikast