Fulvant (Fulvestrant Injection)
Molecular Salt: Fulvestrant Injection
Fulvestrant
Classification - Anticancer Medicine
Fulvestrant?
It is an anticancer medicine widely used for breast cancer in post-menopausal women.
Uses -
HER-2 positive breast cancer
HER-2 negative breast cancer
Breast cancer that is resistant to endocrine therapy.
How does Fulvestrant work?
- Selective Estrogen Receptor Antagonist.
- It inhibits estrogen hormone, which causes cancer cells to grow.
- Stops cancer cell growth.
- Shrink the tumor.
Benefits
- As a preferred second-line option.
- Longer progression-free survival.
- Directly downregulate the receptor, offering complete blockade.
- Has better tolerance and a favorable safety profile.
Precautions -
Carefully administer to patients with -
- Blood disorders,
- Hypersensitive individuals,
- Hepatic impairment,
- Children, pregnant or lactating mothers.
- Elderly patients who are at risk of osteoporosis.
- Vitamin D or Calcium deficiency
Adverse drug effects
- Risk of bleeding,
- Sore throat,
- Mouth sores,
- Upset stomach,
- Nausea,
- Loss of appetite,
- Headache, and
- Tiredness.
- Flushing or redness of the skin at the site of injection.
Serious side effects -
- Hepatotoxicity - yellow coloration of urine, jaundice, hepatitis
- Pulmonary embolism, blood clots
- Severe necrosis
- Gastrointestinal perforation, bleeding
- Fracture or risk of bone demineralization
Important Safety and Monitoring Information
To monitor regularly during the therapy
- Total blood count
- Hepatic functions
- Kidney functions
- Local tissue necrosis
- Risks of bleeding
- Thromboembolic events
Contraindications -
Allergy or hypersensitivity to the drug components.
Breastfeeding mothers
Pregnant women
Warning:
To be used under medical supervision, an oncologist specialist.
Storage
It is to be stored at 2-8 degrees Celsius, protected from light.
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Arechar Healthcare
Injection (250 mg)
Single Pack Unit
Store below 30°C in a dry place
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Storage Warning: Biological injectables, biosimilars, and active oncology agents are flagged as temperature-sensitive cargo and are packed strictly inside thermal containers coupled with real-time digital temperature tags.