Lapakast -250 mg
Molecular Salt: Lapatinib Ditosylate IP -250mg
Lapakast -250 mg
Composition: Lapatinib Ditosylate IP -250mg
Therapeutic Class: Antineoplastic
What is Lapakast?
Lapakast is an anticancer medicine that is used orally against solid tumors and breast cancers.
Uses of Lapakast –
- Advanced-stage Breast cancer
- Metastatic Breast Cancer
- Lung cancer
How does Lepakast work?
It causes programmed cell death by inhibiting HER-2 and EGFR receptors.
It inhibits signals for cancer cell growth and division.
Common Side-Effects
- Anorexia
- Diarrhea
- Skin rashes, itchiness
- Stomatitis, constipation, and abdominal pain
- Palmar-plantar erythrodysaesthesia
- Pain in the extremity, back pain
- Hair loss
Serious Side-Effects
- Bleeding in the stomach
- Dehydration
- Electrolyte imbalance
- QT prolongation
- Hand and foot syndrome
Toxicities
- Cardiac toxicities
- Hepatotoxicity
- Interstitial Lung Disease
- Pneumonitis
Contraindications
Not to be used in patients –
- Hypersensitive or allergic to the drug or its excipients.
- Breastfeeding mothers
- Pregnant women
Precautions
To be used cautiously in patients with
- Heart disease
- Low blood count
- Liver disease
Warnings
To be used under medical supervision
Important Safety and Monitoring Information
Regular monitoring is crucial for patient safety and treatment efficacy -
- The liver function- AST, ALT, bilirubin, alkaline phosphatase
- Cardiac function- periodic assessment of left ventricular ejection
- Electrolyte balance- potassium, magnesium levels
- GIT disturbances- hydration status
- Regular blood count – Complete blood count
Aprazer Healthcare
Tablets (250mg)
Single Pack Unit
Store below 30°C
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Storage Warning: Biological injectables, biosimilars, and active oncology agents are flagged as temperature-sensitive cargo and are packed strictly inside thermal containers coupled with real-time digital temperature tags.