Lapatinib

Lapatinib

Classification – Anticancer Medicine

What is Lapatinib?

It is an anticancer medicine that works against hormone-sensitive breast cancer.

Uses of Lapatinib

• HER-2 positive breast cancer
• Hormone-sensitive breast cancer

How does Lapatinib work?

• Stops cancer multiplication and growth
• Shrinks the tumor

Common Side Effects

• Diarrhea
• Nausea
• Skin rashes
• Reduced appetite
• Hand–foot syndrome
• Liver dysfunction
• Heart dysfunction

Serious Side Effects

• Severe diarrhea
• Dehydration
• Liver toxicity
• Shortness of breath
• Decreased heart function
• Symptoms worsen due to tumor changes

Precautions

• Liver disorders
• Heart disorders
• Lung disease
• People prone to dehydration
• Caution when used with other drugs like ketoconazole, phenytoin
• Elderly

Contraindications

• Should not be used in pregnant women and breastfeeding mothers
• Hypersensitivity or allergy to drug components

Warnings

To be used under medical prescription.

Safety instructions

• Maintain contraception during the treatment
• Avoid live vaccines (MMR, Varicella) due to a compromised immune system

Important Monitoring Considerations

Monitor for-

• Liver functions
• Heart functions
• Hydration status
• Electrolyte balance

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