Anti Cancer Drugs
Hepatitis C
Meds for HIV
Ayurvedic Medicine
Transplant Medicine
Erectile Dysfunction
Respiratory System
+91-9811604444/ 9811604424/ 9999064250 
8(800)100-47-90
Velakast (sofosbuvir 400mg + velpatasvir 100mg) is a fixed-dose combination (FDC) drug used in patients with chronic hepatitis C viral (HCV) infection with genotype 1 to 6 in adults. With 93-99% of response against HCV cells depending on the genotype and the levels of cirrhosis, the FDC drug in a combined-action reduces the multiplication of HCV cells.
Sofosbuvir inhibits NS5B protein whereas velpatasvir inhibits NS5A protein. These proteins help in the replication process and their inhibition ensures that viral toll on the body is lessened.
Velakast (sofosbuvir + velpatasvir) is taken in a form an FDC i.e. 1 tablet (sofosbuvir + velpatasvir combination) once daily for 12 weeks. It is taken orally and the dose is not limited to the food consumption.
Suggested dosage of Velakast (sofosbuvir + velpatasvir) in patients with genotypes 1 to 6 HCV:
| HCV disease type | Dosage | |
| No cirrhosis and cirrhosis with a functional system | Velakast (sofosbuvir + velpatasvir) | |
| Cirrhosis with an unfunctional system | Velakast (sofosbuvir + velpatasvir) plus ribavirin | |
| Other properties | ||
| Properties | Sofosbuvir | Velpatasvir |
| Binding rate | Lower- 61% to 65% | Higher- 99% |
| Absorption within the system | 30 minutes to 2 hours | 3 hours |
| Half-life | 40 minutes to 27 hours | 15 hours |
Side-effects of Velakast (sofosbuvir 400mg + velpatasvir 100mg):
With their decent safety profile, the FDC combination is deemed to have more benefits over other anti-HCV combinational drugs. The side-effects are minor with headache and tiredness (Fatigue) being the most common ones whereas skin rashes and depression are the uncommon ones. 
Serious side-effects: Slow heart rate (bradycardia)
Other side-effects:
Based on the disease type and individuals, the side-effects of Velakast (sofosbuvir + velpatasvir) may differ. The table below shows side-effects other than the above-mentioned common ones.
| Cirrhosis with a functional system | Without cirrhosis or with compensated cirrhosis |
| Low red blood cell count (Anemia) | Nausea |
| Lack of sleep (Insomnia) | Physical weakness (Asthenia) |
| Diarrhea | Lack of sleep (Insomnia) |
| Nausea | – |
Note: These are not all possible side-effects of Velakast (sofosbuvir 400mg + velpatasvir 100mg), please ask your doctor for more information regarding the same.
Warnings associated with Velakast (sofosbuvir + velpatasvir):
Problems related to liver
- HCV patients should be checked for Hepatitis B viral infection if found velakast (sofosbuvir + velpatasvir) should be immediately stopped
- Other liver problems in association with HCV infection should be taken into consideration and accordingly, the dosage should be modified or restricted
Other issues:
- Patients should be mention if they are suffering from any sort of kidney disease or undergoing dialysis, modification of dosage is required in such cases
- Other severe medical conditions related to heart and brain
Pregnancy-related issues:
If patients are,
- Pregnant or planning to get pregnant
- Breastfeeding or planning to breastfeed
- Male and the partner want to get pregnant (Avoid intercourse without condoms for at least 6 months after the therapy)
Note: We are also exporting to countries: Malaysia, Indonesia, Philippines, Venezuela and Korea.
Kelly Grim –
For the treatment of hepatitis C, this is an excellent medicine. I’m taking it for two months. My health has improved significantly.
Scott Brecker –
Really good medicine for the treatment of hepatitis C.
Walid Hamza –
It is a only medicine work for me. After taking it, I’ve noticed a significant improvement.
Beth Maxwell –
Velakast was recommended by my doctor for the treatment of hepatitis C. Thank you, Gandhi Medicos, for getting it to me on time.
Vlaicu Aurel –
Very effective medicine for Hepatitis C without any side effect.