Sofosbuvir + Velpatasvir

Classification – Hepatitis C Medicine

Sofosbuvir + Velpatasvir combination?

It is a fixed-dose antiviral combination used for Chronic Hepatitis C. It is effective against all major 6 genotypes.

Uses of Sofosbuvir + Velpatasvir combination

  • • Chronic Hepatitis C
  • • HCV-HIV co-infections
  • • Naïve Hepatitis C treatment or /relapsed treatment

Working of Sofosbuvir + Velpatasvir

It mimics natural nucleosides and inhibits RNA replication and multiplication.

Benefits

  • • Pan genotypic coverage (effective against all Hepatitis C strains)
  • • Shorter treatment duration
  • • Can be used in HIV co-infections
  • • Can be used with ribavirin
  • • Effective in advanced liver diseases
  • • In children > 3 years
  • • Post liver transplant
  • • Low resistance risk

Common Side Effects

Nausea, dizziness, headache, digestive issues, tiredness, diarrhea

Serious Side Effects

  • • Severe Bradycardia (when taken with amiodarone)
  • • Causes Hepatitis B reactivation
  • • Severe liver failure
  • • Severe anemia upon use with ribavirin
  • • Depression, mood swings, and confusion

Precautions

To be used cautiously in patients

  • • Kidney disorders
  • • Liver disorder
  • • Heart disorders
  • • Hepatitis B co-infections – cause reactivation
  • • HIV co-infection
  • • When used with ribavirin and amiodarone

Contraindications

  • • Hypersensitive reaction to drug components
  • • Breastfeeding and Pregnant Women

Warning

To be used when prescribed by a medical practitioner.

Not to be used alone for HCV infections.

Important Safety and Monitoring Information

  • • Regular monitoring of hepatic functions
  • • Renal functions
  • • Cardiac functions
  • • Co-infections
  • • Neuropsychiatric adverse reactions

Drug Interactions

  • • Ribavirin and Amiodarone
  • • Anticonvulsant
  • • Antivirals
  • • Cardiovascular medicines
  • • Hypertension medicines
  • • Antacids and PPIs

Gandhi Medicos – Trusted Hepatitis C Medicines

Gandhi Medicos is a specialty care pharmacy trusted worldwide by leading hospitals, healthcare professionals, and clinicians offering affordable genuine medicines.

✅ Why Choose Gandhi Medicos?

  • • 25,000+ satisfied global customers
  • • Choice of preference by leading doctors and hospitals
  • • Delivering to over 50+ countries
  • • WHO-GMP-certified medicines
  • • Extensive Portfolio – including HIV, Hepatitis, and Transplant Therapy

What Sets Gandhi Medicos Apart?

  • • Reliable distribution of branded & generic Hepatitis B and C medicines
  • • Temperature-controlled shipment
  • • Timely response and strong customer support
  • • Collaboration with leading pharmaceutical partners