Dasatinib for Chronic Myeloid Leukemia, Affordable Dasatinib for CML Therapy

Dasatinib

Classification: Anticancer medicine

Dasatinib?

It is an anticancer medicine used for various types of blood cancer.

Uses

Myeloid leukemia (Chronic)
Lymphoblastic leukemia (Acute)

How does it work?

It inhibits the protein that causes wrong signaling and stops the growth of cancer cells.

Common Side Effects

Fluid retention
Lowering of blood count
Nausea
Diarrhea
Skin ulcers and rashes
Serious side-effects
Risk of cardiac arrhythmia
Bone marrow suppression
Pulmonary Arterial Hypertension

Serious Side Effects

Risk of cardiac arrhythmia
Bone marrow suppression
Pulmonary Arterial Hypertension

Contraindications

Not to be used in patients-

Hypersensitivity or allergy to the components of the drug
Breastfeeding mothers
Pregnant women

Precautions

To be cautiously used in patients with –

Bleeding disorder
Cardiovascular diseases
Hepatic, renal impairment
Recent surgery or wound
Disorders of the stomach

Toxicities

Myelosuppression – low blood count
Pleural effusion – shortness of breath, fluid buildup around lungs
Hematological toxicity – bleeding risk, decreased platelet count
Hepatotoxicity – elevated enzymes
QT Prolongation – irregular heartbeats

Warnings

To be used under medical supervision or a doctor’s prescription.

Important Safety and Monitoring Information

Dasatinib requires regular monitoring for hematological functions, blood pressure, liver functions, ECG, regular monitoring of electrolytes.

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