Dolutegravir + Emtricitabine + Tenofovir Alafenamide

Composition-

Dolutegravir (50mg) Emtricitabine (200mg) Tenofovir Alafenamide (25mg)

Classification -

HIV Medicine

Dolutegravir, Emtricitabine, Tenofovir Alafenamide ?

It is widely used as a single-dose regimen against HIV infection that offers better patient compliance and a synergistic effect.

Uses -

HIV -1 infections

How does it work?

Dolutegravir-

It prevents genetic transmission into human immune cells (CD4+ T cells).

Emtricitabine -

It inhibits viral cell multiplication.

Tenofovir Alafenamide -

Stops the formation of viral cell copies

.

Benefits

Powerful control of HIV Well tolerated, Lowers the risk of drug resistance Fewer side-effects Improves immunity Prevent transmission Prevent HIV progression

Common side effects

Insomnia Tiredness Headache Increased weight Dermatological side effects Nausea Diarrhea High levels of cholesterol

Serious side effects

Liver dysfunction Lactic acidosis Increased blood glucose Kidney dysfunctions Neurological side effects - depression / suicidal thoughts

Precautions:

To be used cautiously in People with diabetes Liver disorders Mental health Pregnant women

Drug interactions

Antacids Rifampicin Phenytoin Efavirenz Barbiturates Metformin Iron/calcium supplements

Contraindications

Severe liver dysfunction. Severe renal impairment Hypersensitivity or allergy to drug components. Children under 4 weeks or less than 3kg.

Warnings

To be used under medical prescription Stop treatment by tapering the dose in Hepatitis co-infections

Important Monitoring Considerations

Check for - Liver function - elevated liver enzymes Viral loads (HIV, HBV) Neurological conditions CD4 cell count Renal functions Blood glucose Weight

Gandhi Medicos - Global Standard HIV Medicines

Gandhi Medicos is a 19-year-old trusted HIV medicine distributor and supplier, strengthening access to affordable, high-quality HIV treatments worldwide. ✅ 400+ Ethical Brands ✅ 500+ Trusted Generics ✅ Leading HIV Medicine Antiviral exporter ✅ Supplying to Hospitals, Clinics & HIV Care Centers

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