Eltrombopag Olamine

Classification: Platelet enhancer

Eltrombopag Olamine?

It elevates the low platelet count. It is used in cancer care therapy to reduce chemotherapy side effects.

Uses of Eltrombopag

  • • Chronic immune thrombocytopenic purpura
  • • Aplastic Anemia
  • • Thrombocytopenia related to Hepatitis C
  • • Supportive care in bone marrow suppression

Working of Eltrombopag

It mimics the thrombopoietin hormone and induces platelet secretion.

Common Side Effects of Eltrombopag

  • • Tiredness
  • • Pain in the abdomen
  • • Changes in urine color
  • • Skin rashes
  • • Cough
  • • Vomiting
  • • Nausea

Serious Side Effects

  • • Hepatic toxicity
  • • Thrombosis and stroke
  • • Cataract formation

Contraindications

Not to be used in patients-

  • • Hypersensitivity or allergy to eltrombopag or other drug components
  • • Breastfeeding mothers
  • • Pregnant women

Precautions

To be used cautiously in patients with –

  • • Hepatic impaired functions
  • • Renal impaired functions
  • • Blood disorders
  • • Cardiac patients

Warnings

Prescription drug to be used under medical supervision.

Important Safety and Monitoring Information

  • • Monitor for hepatotoxicity
  • • Liver function tests
  • • Regular CBC – platelet count
  • • Cardiac functions- thromboembolic events due to overproduction of platelets.
  • • Ophthalmic functions

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