Ivabradine
Classification – Heart Medicine
Ivabradine?
It is a cardiovascular medicine used to treat heart failure.
Uses
- • Chronic heart failure
- • Control heart rate
- • Orthostatic tachycardia
- • Chest pain
Working of Ivabradine
It works on the Sino-Atrial node, slowing down the fast heart rate.
Common Side Effects
- • Slows down the heart rate
- • Visual effects
- • Dizziness
- • Headaches
- • Tiredness
Serious Side Effects
- • Severely slow heart rate
- • Irregular heart rhythm
- • Low blood pressure
- • Worsened angina
Benefits
- • Lowers heart rate without lowering blood pressure
- • Reduces chest pain
- • Reduces the risk of hospitalization
- • Improves exercise tolerance
- • Well tolerated
- • Can be used with other cardiac medicines
Precautions
- • Atrial fibrillation
- • Severe bradycardia
- • Severely low blood pressure
- • Liver disorders
- • Elderly patients
- • Conduction abnormalities
Contraindications
- • Sino-atrial block
- • 3rd degree heart block
- • External pacemaker
- • Unstable heart failure
- • Use with other antiarrhythmic medications
- • Allergy to the drug components
- • Pregnant and breastfeeding women
Warnings
To be used under medical prescription.
Important Monitoring Considerations
Regularly monitor –
- • Heart rate
- • Heart rhythm
- • Blood pressure
- • Effects on the eye
Drug Interactions
- • Antifungals
- • Rifampicin
- • Phenytoin
- • Antiarrhythmic
- • Beta blockers
- • QT prolongation
- • Diuretics
- • Barbiturates
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