Mitomycin

Composition: Mitomycin 10mg

Therapeutic class: It is an Anti-neoplastic, an antibiotic

What is Mitomycin?

Mitomycin is used as an anticancer medicine against many cancers and solid tumors.

Uses of Mitomycin

Stomach cancer

Pancreatic cancer

Ovarian cancer

Breast cancer

Uterus cancer

Small cell lung cancer

How does Mitomycin work?

It gets attached to DNA, forms cross-links in the DNA, inhibits replication, and division, causing cancer cell death.

Common side effects

Nausea

Bone marrow suppression

Mouth ulcers

Alopecia

Skin rashes

Serious side effects

High doses can lead to -

Anemia

Low platelet count

Lung scarring

Kidney damage

Liver toxicity

Shortness of breath

Fast irregular heartbeat

Precautions

To be cautiously used in -

Pre-existing liver disorder

Kidney disorder

Bleeding disorders

Severe infection

Elderly patients

Mylosuppressant therapy

Respiratory infection

Asthma

Anemic

Contraindications

Not to be used if any previous allergy or hypersensitivity to Mitomycin or any excipients.

Breastfeeding mothers

Pregnant women

Warning:

To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.

Important safety and monitoring information

Monitor-

Total blood count

Renal functions

Pulmonary functions

Hepatic functions

Local tissue necrosis

Storage

It should be stored at 2-8 degrees Celsius, protected from light.

Administration Instructions

To be administered as a slow IV infusion.

Avoid IV push or rapid bolus.

To be used immediately after reconstitution.