Nintenanib-150mg

Classification: Anticancer and Anti-fibrotic

Nintedanib

Nintedanib is an oncology medicine that has anti-fibrotic properties and is widely used for various diseases of the lungs and cancers.

Uses

  • • Non-small cell lung cancer
  • • Pulmonary fibrosis
  • • Systemic sclerosis of the lungs

Working of Nintedanib

  • • It inhibits growth factors
  • • It inhibits angiogenesis and fibrosis

Common Side Effects

  • • Diarrhea
  • • Nausea
  • • Vomiting
  • • Liver dysfunction
  • • Decreased weight
  • • Reduced appetite
  • • Headache
  • • Tiredness

Serious Side Effects

  • • Gastrointestinal bleeding
  • • Liver toxicity
  • • Thromboembolic events
  • • High blood pressure
  • • Delayed wound healing
  • • GIT perforation

Precautions

To be cautiously used in –

  • • Severe liver disorders
  • • Bleeding disorders
  • • Heart disorders
  • • Elderly
  • • Gastrointestinal disorders
  • • Before and after surgery

Contraindications

  • • Allergy or hypersensitivity to drug components
  • • Breastfeeding mothers
  • • Pregnant women

Warning

To be used under medical prescription only

Safety and Monitoring information

Monitor –

  • • Liver functions
  • • Cardiac functions
  • • Blood pressure
  • • Total blood count

Use contraception for 3 months of therapy use.

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