Paclitaxel 260mg Injection
Classification: Anticancer Medicine
What is Paclitaxel?
It is an anticancer medicine that is used for various advanced cancers.
Uses of Paclitaxel
- • Breast cancer
- • Ovarian cancer
- • AIDS related sarcoma
- • Non-small cell lung cancer
- • Pancreatic cancer
- • Head and neck cancer
How does it work?
- • It inhibits the splitting of double-stranded DNA, inhibiting its replication and multiplication.
Common Side Effects of Paclitaxel
- • Tiredness
- • Hair loss
- • Increases the risk of infections
- • Indigestion – diarrhea, constipation
- • Hypotension
- • Mouth ulcers
- • Muscle and joint pain
- • UTI
- • Anemia
- • Numbness of limbs, tingling in hands, fingers
Serious Side Effects of Paclitaxel
- • Bone Marrow Suppression
- • Slow heartbeat
- • Shortness of breath
- • Blood clot
- • Chest pain
- • Liver toxicity
- • Local tissue injury
- • Pain in the abdomen
Precautions
To be used cautiously in patients with –
- • Liver disorders
- • Renal disorders
- • Hypertension patients
- • Elderly patients
- • Pre-existing infections
- • Immune-compromised patients
- • Adjuvant to myelo-suppressive treatments
Contraindications
- • Allergy or hypersensitivity to Paclitaxel
- • Breastfeeding mothers
- • Pregnant women
Warnings
To be used as prescribed by the doctor.
Important Safety and Monitoring Information
Regularly monitor –
- • Total blood count
- • Liver functions
- • Infection risks
- • Heart functions
- • Neuropathy
Storage of Paclitaxel Injection
Keep at 2–8°C and protect from light.
Administration Instructions
- • Use as a slow IV infusion only
- • Do not give as an IV push/bolus
- • To be used immediately after reconstitution
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