Paclitaxel IP 100 mg

Paclitaxel IP 100 mg

Classification: Anticancer Medicine

What is Paclitaxel IP 100mg?

Paclitaxel is an anticancer medicine that is combined with Human Albumin to enhance its solubility and binding to the blood cells. It reduces the need for solvents to dissolve paclitaxel.

Uses of Paclitaxel

• • Advanced Stage Breast Cancer
• • Advanced-stage Pancreatic Cancer
• • (Non-small cell) lung cancer

How Does Paclitaxel Work?

• • It binds to the tubulin protein.
• • Arrest the mitotic phase, inhibiting cell division.
• • Stops cancer multiplication and causes cell death.

Common Side-Effects

• • Nausea
• • Vomiting
• • Mouth ulcers
• • Loss of hunger
• • Skin rashes, itchiness
• • Tiredness
• • Hair loss
• • Swelling of the ankles

Toxicities

• • Myelo-suppression
• • Gastrointestinal toxicity
• • Thrombocytopenia
• • Cardiac toxicity

Precaution

To be cautiously used in patients with –

• • Irregular heartbeat
• • Liver disease
• • Low blood count
• • Breathing disorder

Contraindications

Not to be used on people –

• • Allergic to Paclitaxel
• • Breastfeeding women
• • Pregnant women

Warning

To be used under medical supervision, administered slowly over 30 minutes.

Important Safety Information

It should be regularly monitored for –

• • Liver functions
• • Blood count
• • Renal functions
• • Cardiac function

Storage of Paclitaxel Injection

2-8 degrees Celsius storage required and protected from light. The reconstituted solution is to be used immediately.

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