Pirfenidone

Classification - Respiratory Medicine

What is Pirfenidone?

It is an antifibrotic drug used against scarring of the lung tissues.

Uses

Pulmonary Fibrosis

Liver fibrosis

Systemic sclerosis

Working of Pirfenidone

It reduces inflammation and prevents lung scars.

Benefits

It's well tolerated

Slows down lung scarring

Delays disease progression

Preserves Lung capacity

Common side effects

Nausea

Diarrhea

Skin rashes due to photosensitivity

Serious side effects

Severe hepatic dysfunction

Jaundice

Gastric bleeding

Tiredness

Blistering or peeling of skin

Precautions:

To be used cautiously in patients with -

Liver disorders

Renal disorders

Elderly patients

Pre-existing skin infections

Smoking

Alcohol

Gastrointestinal disorders

Warnings

To be used as prescribed by the doctor.

Contraindications

Severe Liver dysfunction

Severe renal impairment

Allergy to drug components

Important safety and monitoring information

Regularly monitor -

Total blood count,

Liver functions

Infection risks,

Heart functions, and

Neuropathy

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