Ribavirin

Classification: Hepatitis C medicines

What is Ribavirin?

Its antiviral nature is used against Hepatitis C treatment.

Uses of Ribavirin

Chronic Hepatitis C

Respiratory Viral Disease

Working of Ribavirin

It changes the viral cell integrity.

Inhibits both RNA and DNA multiplication and replication.

Benefits

It can be used in combination with other antivirals.

Boost the effectiveness of other antivirals.

Lowers the risk of relapse

Effective against various viral RNA /DNA

Can be used for Respiratory viruses in infants and immunocompromised individuals

Common Side Effects

Nausea,

Dizziness,

Headache,

Digestive issues,

Tiredness,

Diarrhea.

Serious Side Effects

Destroying red blood cells causes severe Anemia.

Pancreatitis

Hepatic toxicity- Avoid alcohol while treatment

Neuropsychiatric condition- depression, confusion

Cardiac toxicity - heart attack, strokes

Suppresses the immune system

Precautions

To be cautiously used in patients with -

Liver disorders

Kidney disorder

Anemic

Severe psychiatric illness

Autoimmune disease

Severe heart disease

And co-administration with another drug like zivoduvine.

Contraindications

Allergy or hypersensitivity to any drug component.

Breastfeeding mothers

Pregnant women

Warning

Take only when recommended by the doctor.

Important Safety and Monitoring Information

Regular monitoring of -

Hepatic functions,

Renal functions,

Cardiac functions,

Co-infections, and neuropsychiatric adverse reactions.

Drug interactions -

Zidovudin, Didanosine, Azathioprin -

It increases the risk of a fall in RBC count and lactic acidosis.

Antacids - They may impair antacid absorption.

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