Tacrolimus
Classification - Organ Transplant Medicine
What is Tacrolimus?
Tacrolimus is an organ transplant medicine, widely used for post-transplant care and prophylaxis of organ rejection.
Best-selling Transplant Medicine- Xgraf -1
Uses of Tacrolimus
Prophylaxis for organ transplant.
Post-transplant therapy
Kidney transplant
Liver transplant
Heart transplant
Working of Tacrolimus -
It suppresses the activity of T cells and lowers the immune response.
Accepts the organ transplants
Benefits:
Faster onset
Potent immune-suppression
Long-term graft survival
Common side effects
Increases creatinine
Skin rashes
Headache
GIT upset
Nausea,
Diarrhea
High calcium levels
Low potassium levels
Tiredness
Serious side effects
Renal toxicity
Severe infections
Seizures, encephalopathy
Bone marrow suppression
Metabolic dysfunctions
Cardiovascular side effects
Arrhythmias, high blood pressure
Lymph proliferative disorder (PTLD)
Precautions:
To be used cautiously used in-
Elderly Patients
Bleeding disorders
Liver disorders
Kidney diseases
Active infections- HIV, Hepatitis
Diabetics
Hypertension patients
Neurological disorders
Safety instructions
Maintain contraception during the treatment.
Avoid live vaccines (MMR, Varicella) due to a compromised immune system.
Contraindications
Pregnant women and breastfeeding mothers.
Hypersensitivity or allergic reaction to the drug or its excipients.
Warnings
To be used under medical prescription.
Drug Interactions
Antiviral
Antibiotics
TB medicines
And other immune suppressants
Cardiovascular drugs -calcium channel blockers
Antifungal
Grapefruit juice
Important Monitoring Considerations
Monitor for -
Total blood count
Liver and kidney functions
Neurological functions
Blood pressure, blood glucose
Cardiac functions
Dose Monitoring is required.
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Formulations based on "Tacrolimus" (33)
Pangraf 1 Capsule
Tacrolimus (1mg)
Product Name Pangraf 1 Capsule Composition Tacrolimus (1mg) Dose/Strength 1mg Form Capsule Manufactured By Panacea Biotec Ltd packaging Size 10 capsules in 1 strip Prescription Required Storage Store below 30?C
Tacrograf 1 Capsule
Tacrolimus (1mg)
Product Name Tacrograf 1 Capsule Composition Tacrolimus (1mg) Dose/Strength 1mg Form Capsule Manufactured By Biocon packaging Size 10 capsules in 1 strip Prescription Required Storage Store below 30?C
Tacsant 1mg Capsule
Tacrolimus (1mg)
Product Name Tacsant 1mg Capsule Composition Tacrolimus (1mg) Dose/Strength 1mg Form Capsule Manufactured By Novartis India Ltd packaging Size 10 capsules in 1 strip Prescription Required Storage Store below 30?C
Tacroren 1 Capsule
Tacrolimus (1mg)
Product Name Tacroren 1 Capsule Composition Tacrolimus (1mg) Dose/Strength 1mg Form Capsule Manufactured By La Renon Healthcare Pvt Ltd Packaging Size 10 capsules in 1 strip Prescription Required Storage Store below 30?C
Biomus 1 Capsule
Tacrolimus (1mg)
Product Name Biomus 1 Capsule Composition Tacrolimus (1mg) Dose/Strength 1 mg Form Capsule Manufactured By Alniche Life Sciences Pvt Ltd Packaging Size 10 capsules in 1 strip Prescription Required Storage Store below 30 °C
Vingraf 1 Capsule
Tacrolimus (1mg)
Product Name Vingraf 1 Capsule Composition Tacrolimus (1 mg) Dose/Strength 1mg Form Capsule Manufactured By Emcure Pharmaceuticals Ltd Packaging Size 10 capsules in 1 strip Prescription Required Storage Store below 30?C
Takfa 1 Capsule
Tacrolimus (1mg)
Product Name Takfa 1 Capsule Composition Tacrolimus (1mg) Dose/Strength 1mg Form Capcule Manufactured By Intas Pharmaceuticals Ltd Packaging Size 10 capsules in 1 strip Prescription Required Storage Store below 30?C
Tacromus 1 Capsule
Tacrolimus (1mg)
Product Name Tacromus 1 Capsule Composition Tacrolimus (1mg) Dose/Strength 1mg Form Capsule Manufactured By Zydus Cadila Packaging Size 10 capsules in 1 strip Prescription Required Storage Store below 30?C
Xgraf 1 Capsule
Tacrolimus (1mg)
Product Name Xgraf 1 Composition Tacrolimus (1mg) Dose/Strength 1mg Form Capsule Manufactured By Aprazer Healthcare Pvt Ltd Packaging Size 10 capsules in 1 strip Prescription Required Storage Store below 30?C
Prograf 1mg Hard Capsule
Tacrolimus (1mg)
Product Name Prograf 1mg Hard Capsule Composition Tacrolimus Dose/Strength 1mg Form Capsules Manufactured By Astellas Pharma Inc Packaging Size 10 capsules in 1 strip Prescription Required Storage Store below 30°C
Xgraf 0.5 Capsule
Tacrolimus (0.5mg)
Product Name Xgraf 0.5 Composition Tacrolimus Dose/Strength 0.5mg Form Tablets Manufactured By Aprazer Packaging Size 6×10 Tablets Prescription Required Storage Store below 30°C
Pangraf 2 Capsule
tacrolimus (2.0mg)
Product Name Pangraf 2 Composition Tacrolimus Dose/Strength 2mg Form Capsules Manufactured By Panacea Biotec Ltd Packaging Size 3×10 Tablets Prescription Required Storage Store below 30°C
Imunotac 2mg Capsule
Tacrolimus (2mg)
Product Name Imunotac 2mg Composition Tacrolimus Dose/Strength 2mg Form Capsules Manufactured By RPG Life Sciences Ltd Packaging Size 10×10 Capsules Prescription Required Storage Store below 30°C
Fujigraf 2mg Capsule
Tacrolimus (2mg)
Product Name Fujigraf 2 Composition Tacrolimus Dose/Strength 2mg Form Capsules Manufactured By Hospimax Healthcare Pvt Ltd Packaging Size 6×10 Tablets Prescription Required Storage Store below 30°C
Tacren 2 Capsule
Tacrolimus (2mg)
Product Name Tacren 2 Capsule Composition Tacrolimus Dose/Strength 2mg Form Capsules Manufactured By Chemo Healthcare Pvt Ltd Prescription Required Storage Store below 30°C
Biomus 2mg Capsule
Tacrolimus (2mg)
Product Name Biomus 2 Composition Tacrolimus Dose/Strength 2 mg Form Capsules Manufactured By Alniche Life Sciences Pvt Ltd Packaging Size 1×10 Capsules Prescription Required Storage Store below 30°C
Vingraf 2mg Capsule
Tacrolimus (2mg)
Product Name Vingraf 2 Composition Tacrolimus Dose/Strength 2mg Form Capsules Manufactured By Emcure Pharmaceuticals Ltd packaging Size 6×10 Capsules Prescription Required Storage Store below 30°C
Takfa 2 Capsule
Tacrolimus (2mg)
Product Name Takfa 2 Capsule Composition Tacrolimus (2mg) Dose/Strength 2mg Form Capsules Manufactured By Intas Pharmaceuticals Ltd Packaging Size 6×10 Capsules Prescription Required Storage Store below 30°C
Tacromus 2mg Capsule
Tacrolimus (2mg)
Product Name Tacromus 2 Composition Tacrolimus (2mg) Dose/Strength 2mg Form Capsules Manufactured By Zydus Cadila Packaging Size 6×10 Capsules Prescription Required Storage Store below 30°C
Xgraf 2 Capsule
Tacrolimus (2mg)
Product Name Xgraf 2 Composition Tacrolimus (2mg) Dose/Strength 2mg Form Capsules Manufactured By Aprazer Healthcare Pvt Ltd packaging Size 6×10 Capsules Prescription Required Storage Store below 30°C
Nefgraf 2mg Capsule
Tacrolimus (2mg)
Product Name Nefgraf 2mg Capsule Composition Tacrolimus (2mg) Dose/Strength 2mg Form Capsules Manufactured By Cmg Biotech Pvt Ltd packaging Size 5×5 Capsules Prescription Required Storage Store below 30°C
Tacrol 1mg Capsule
Tacrolimus (1mg)
Product Name Tacrol 1mg Capsule Composition Tacrolimus (1mg) Dose/Strength 1mg Form Capsule Manufactured By Mediart Lifesciences Pvt Ltd Packaging Size 10 capsules in 1 strip Prescription Required Storage Store below 30°C
Tacromus 0.5 Capsule
Tacrolimus (0.5mg)
Product Name Tacromus-0.5 Composition Tacrolimus Dose/Strength 0.5mg Form Capsules Manufactured By Zydus Cadila Packaging Size 6×10 Capsules Prescription Required Storage Store below 30°C
Tacroren 0.5 Capsule
Tacrolimus (0.5mg)
Product Name Tacroren 0.5 Capsule Composition Tacrolimus Dose/Strength 0.5mg Form Capsule Manufactured By La Renon packaging Size 10×10 Capsules Prescription Required Storage Store below 30°C
Takfa 0.5 Capsule
Tacrolimus (0.5mg)
Product Name Takfa 0.5 Capsule Composition Tacrolimus Dose/Strength 0.5mg Form Capsules Manufactured By Intas Pharmaceuticals Ltd Packaging Size 6×10 Capsules Prescription Required Storage Store below 30°C
Prograf 0.5mg Capsule
Tacrolimus (0.5mg)
Product Name Prograf 0.5mg Capsule Composition Tacrolimus Dose/Strength 0.5mg Form Capsules Manufactured By Astellas Pharma Inc packaging Size 5×10 Capsules Prescription Required Storage Store below 30°C
Vingraf 0.5 Capsule
Tacrolimus (0.5mg)
Product Name Vingraf 0.5 Capsule Composition Tacrolimus Dose/Strength 0.5mg Form Capsule Manufactured By Emcure Pharmaceuticals Ltd Packaging Size 6× 10 Capsules Prescription Required Storage Store below 30°C
Tacsant 0.5mg Capsule
Tacrolimus (0.5mg)
Product Name Tacsant 0.5mg Capsule Composition Tacrolimus Dose/Strength 0.5mg Form Capsule Manufactured By Novartis India Ltd packaging Size 5×10 Capsules Prescription Required Storage Store below 30?C
Tacrograf 0.5 Capsule
Tacrolimus (0.5mg)
Product Name Tacrograf 0.5mg Composition Tacrolimus Dose/Strength 0.5mg Form Capsules Manufactured By Biocon Packaging Size 10×10 Tablets Prescription Required Storage Store below 30°C
Tacrocord 0.5 Capsule
Tacrolimus (0.5mg)
Product Name Tacrocord 0.5 Composition Tacrolimus Dose/Strength 0.5mg Form Capsules Manufactured By Concord Biotech Packaging Size 6×10 Tablets Prescription Required Storage Store below 30°C
Rolitrans 0.5mg Capsule
Tacrolimus (0.5mg)
Product Name Rolitrans 0.5 Composition Tacrolimus Dose/Strength 0.5mg Form Capsules Manufactured By Cipla packaging Size 10 Capsules Prescription Required Storage Store below 30°C
Pangraf 0.5 Capsule
Tacrolimus (0.5mg)
Product Name Pangraf 0.5 Capsule Composition Tacrolimus (0.5mg) Dose/Strength 0.5mg Form Capsule Manufactured By Panacea Biotec Ltd packaging Size 10 capsules in 1 strip Prescription Required Storage Store below 30°C
Tacrograf 2 Capsule
tacrolimus (2.0mg)
Product Name Tacrograf 2mg Composition Tacrolimus(2mg) Dose/Strength 2mg Form Capsules Manufactured By Biocon Packaging Size 5×10 Tablets Prescription Required Storage Store below 30°C