Emtricitabine
Emtricitabine ,Tenofovir,and Efavirenz
Composition -
Emtricitabine -200mg
Tenofovir-300mg
Efavirenz- 600mg
Classification - HIV Medicine
Why Emtricitabine + Tenofovir + Efavirenz Combination?
It is the drug combination therapy used as primary treatment for HIV-1 infection.
Uses -
HIV-1 infections
Post-exposure prophylaxis treatment
Working of the Emtricitabine + Tenofovir + Efavirenz Combination
The potent combination inhibits different steps of viral replication and multiplication.
It offers synergistic viral suppression.
Common side effects
Headache
Dizziness
Insomnia, nightmares
GIT upset- diarrhea, nausea, vomiting
Skin rashes
Muscle pain
Serious side effects
Neurological side effects (efavirenz) - depression, anxiety, seizures
Liver dysfunctions- jaundice, hepatitis
Fluid retention, changes in urine
Buildup of lactic acid in the blood
Bone loss - fractures, bone pain
Hypersensitive reaction - fever, rash, swollen lymph nodes
Precautions
To be used cautiously in people with
Neuropsychiatric disorders
Kidney diseases
Liver diseases
Pregnancy
Breastfeeding
Elderly patients
Osteoporosis or people with a bone disorder
Other drugs- risk of drug interactions
Contraindications
Severe liver dysfunction.
Severe kidney diseases
Hypersensitivity or allergy to the drug components
Warnings
To be used under medical prescription.
In hepatitis co-infection, stop treatment by tapering the dose.
Important Monitoring Considerations
Check for -
Lactic acidosis
Liver function - elevated liver enzymes
Kidney functions
Viral loads (HIV, HBV)
Bone health
Neurological condition
Lipid profile and sugar levels
Drug interactions
Anticonvulsant
Antifungals
Cholesterol medicines- statins
Anti-tubercular
NSAIDs and other nephrology drugs
Psychiatric medicines- sedatives, antidepressants
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Formulations based on "Emtricitabine" (7)

Virarazer
Tenofovir disoproxil fumarate 300mg + Efavirenz 600mg + Emtricitabine 200mg
Product Name Virarazer Composition Tenofovir disoproxil fumarate 300mg + Efavirenz 600mg + Emtricitabine 200mg Dose/Strength 300 mg/ 600mg/ 200mg Packaging Size 30 Tablets Manufactured By Aprazer Healthcare Prescription Required Storage Store below 30°C

Tenof EM
Tenofovir Disoproxil-Emtricitabine
Product Name Tenof EM Composition Tenofovir disoproxil fumarate + Emtricitabine Manufactured By Hetero Healthcare Limited Dose/Strength 300 mg/200 mg Packaging Size 30 Tablets Prescription Required Storage Store below 30°C

Spegra 30 Tablets / 90 Tablets
Dolutegravir + Emtricitabine + Tenofovir Alafenamide
Product Name Spegra Composition Dolutegravir (50mg) + Emtricitabine (200mg) + Tenofovir Alafenamide (25mg) Form Tablet Packaging Size 30 TABLETS Packaging Type BOTTLE Indications ANTI HIV

Trustiva
Tenofovir Disopoxil-Efavirenz-Emtricitabine
Product Name Trustiva Composition Tenofovir Disoproxil Fumarate 300mg, + Efavirenz 600mg + Emtricitabine 200mg Dose/Strength 300 mg/600 mg/200 mg Packaging Size 30 Tablets Manufactured By Hetero Healthcare Prescription Required Storage Store below 30°C

Viraday
Tenofovir Disopoxil-Efavirenz-Emtricitabine
Product Name Viraday Composition Efavirenz IP 600 mg, Emtricitabine IP 200mg & Tenofovir Disoproxil Fumarate IP 300mg Packaging Size 30 Tablets Manufactured By Cipla Prescription Required Storage Store below 30°C

Taffic Tablet
Bictegravir 50mg, Emtricitabine 200mg, Tenofovir Alafenamide 25mg
Product Name TAFFIC Tablets Composition Bictegravir 50mg, Emtricitabine 200mg, Tenofovir Alafenamide 25mg Manufactured By Hetero Healthcare Limited Packaging Size 30 Tablets Treatment HIV Form Tablet

Spegra 90 Tablets
Dolutegravir + Emtricitabine + Tenofovir Alafenamide
Product Name Spegra Composition Dolutegravir (50mg) + Emtricitabine (200mg) + Tenofovir Alafenamide (25mg) Form Tablet Packaging Size 90 TABLETS Packaging Type BOTTLE Indications ANTI HIV
