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Active Chemical Molecule

Emtricitabine

Emtricitabine ,Tenofovir,and Efavirenz

Composition -

Emtricitabine -200mg

Tenofovir-300mg

Efavirenz- 600mg

Classification - HIV Medicine

Why Emtricitabine + Tenofovir + Efavirenz Combination?

It is the drug combination therapy used as primary treatment for HIV-1 infection.

Uses -

HIV-1 infections

Post-exposure prophylaxis treatment

Working of the Emtricitabine + Tenofovir + Efavirenz Combination

The potent combination inhibits different steps of viral replication and multiplication.

It offers synergistic viral suppression.

Common side effects

Headache

Dizziness

Insomnia, nightmares

GIT upset- diarrhea, nausea, vomiting

Skin rashes

Muscle pain

Serious side effects

Neurological side effects (efavirenz) - depression, anxiety, seizures

Liver dysfunctions- jaundice, hepatitis

Fluid retention, changes in urine

Buildup of lactic acid in the blood

Bone loss - fractures, bone pain

Hypersensitive reaction - fever, rash, swollen lymph nodes

Precautions

To be used cautiously in people with

Neuropsychiatric disorders

Kidney diseases

Liver diseases

Pregnancy

Breastfeeding

Elderly patients

Osteoporosis or people with a bone disorder

Other drugs- risk of drug interactions

Contraindications

Severe liver dysfunction.

Severe kidney diseases

Hypersensitivity or allergy to the drug components

Warnings

To be used under medical prescription.

In hepatitis co-infection, stop treatment by tapering the dose.

Important Monitoring Considerations

Check for -

Lactic acidosis

Liver function - elevated liver enzymes

Kidney functions

Viral loads (HIV, HBV)

Bone health

Neurological condition

Lipid profile and sugar levels

Drug interactions

Anticonvulsant

Antifungals

Cholesterol medicines- statins

Anti-tubercular

NSAIDs and other nephrology drugs

Psychiatric medicines- sedatives, antidepressants

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Formulations based on "Emtricitabine" (6)

Virarazer
HIVVerified Supply

Virarazer

Tenofovir disoproxil fumarate 300mg + Efavirenz 600mg + Emtricitabine 200mg

Product Name Virarazer Composition Tenofovir disoproxil fumarate 300mg + Efavirenz 600mg + Emtricitabine 200mg Dose/Strength 300 mg/ 600mg/ 200mg Packaging Size 30 Tablets Manufactured By Aprazer Healthcare Prescription Required Storage Store below 30°C

Specialty BrandAprazer Healthcare
Unit DosageTablet (300 mg/ 600mg/ 200mg)
Clinical SourceAprazer Healthcare
Temp Tracked: Store below 30°C
Inspect
Tenof EM
HIVVerified Supply

Tenof EM

Tenofovir Disoproxil-Emtricitabine

Product Name Tenof EM Composition Tenofovir disoproxil fumarate + Emtricitabine Manufactured By   Hetero Healthcare Limited Dose/Strength 300 mg/200 mg Packaging Size 30 Tablets Prescription Required Storage Store below 30°C

Specialty BrandHetero Healthcare
Unit DosageTablet (300 mg/200 mg)
Clinical SourceHetero Healthcare
Temp Tracked: Store below 30°C
Inspect
Spegra 30 Tablets / 90 Tablets
HIVVerified Supply

Spegra 30 Tablets / 90 Tablets

Dolutegravir + Emtricitabine + Tenofovir Alafenamide

Product Name Spegra Composition Dolutegravir (50mg) + Emtricitabine (200mg) + Tenofovir Alafenamide (25mg) Form Tablet Packaging Size 30 TABLETS Packaging Type BOTTLE Indications ANTI HIV  

Specialty BrandEmcure
Unit DosageTablet (50 mg)
Clinical SourceEmcure
Temp Tracked: Store below 30°C in a dry place
Inspect
Trustiva
HIVVerified Supply

Trustiva

Tenofovir Disopoxil-Efavirenz-Emtricitabine

Product Name Trustiva Composition Tenofovir Disoproxil Fumarate 300mg, + Efavirenz 600mg +  Emtricitabine 200mg Dose/Strength 300 mg/600 mg/200 mg Packaging Size 30 Tablets Manufactured By Hetero Healthcare Prescription Required Storage Store below 30°C

Specialty BrandHetero Healthcare
Unit DosageTablet (300 mg/600 mg/200 mg)
Clinical SourceHetero Healthcare
Temp Tracked: Store below 30°C
Inspect
Viraday
HIVVerified Supply

Viraday

Tenofovir Disopoxil-Efavirenz-Emtricitabine

Product Name  Viraday Composition  Efavirenz IP 600 mg, Emtricitabine IP 200mg & Tenofovir Disoproxil Fumarate IP 300mg Packaging Size  30 Tablets Manufactured By     Cipla Prescription  Required Storage  Store below 30°C

Specialty BrandCipla
Unit DosageTablet (600 mg)
Clinical SourceCipla
Temp Tracked: Store below 30°C
Inspect
Spegra 90 Tablets
HIVVerified Supply

Spegra 90 Tablets

Dolutegravir + Emtricitabine + Tenofovir Alafenamide

Product Name Spegra Composition Dolutegravir (50mg) + Emtricitabine (200mg) + Tenofovir Alafenamide (25mg) Form Tablet Packaging Size 90 TABLETS Packaging Type BOTTLE Indications ANTI HIV  

Specialty Brand
Unit DosageTablet (50 mg)
Clinical SourceGandhi Medicos
Temp Tracked: Store below 30°C in a dry place
Inspect

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