Gemcitabine
Classification - Anticancer
Gemcitabine?
It is an anticancer medicine, listed as an essential medicine by the WHO.
Uses of Gemcitabine -
Advanced-stage ovarian cancer
Breast cancers
Pancreatic cancer
Lung cancer
Bladder cancer
How does it work?
Gemcitabine mimics cancer DNA bases, inhibiting the chain elongation process.
Stops cancer cell DNA multiplication or growth, causing cell death.
Common side-effects
Nausea
GIT upset - diarrhea, constipation
Skin rashes
Low platelets
Anemia
Risk of infections
Serious side effects
Respiratory dysfunction
Hepatic-toxicity -elevated liver enzymes
Bleeding
Shortness of breath
Fast irregular heartbeat
Change in urine color and volume
Precautions:
To be cautiously used in -
Renal dysfunction
Liver disorder
Elderly patients
Respiratory disorders
Radiation therapy patients
Contraindications
Allergy or hypersensitivity to gemcitabine or any drug components
Breastfeeding mothers
Pregnant women
Warnings
To be used under the supervision of a practitioner or doctor.
Important safety and monitoring information
Regularly monitor blood count, hepatic, manage infection risks, respiratory functions, and renal functions.
Check for fluid retention, hypotension
Capillary leak and immediate swelling
Storage
To be stored at 2-8 degrees Celsius.
Protected from light.
Administration Instructions
To be administered a slow IV infusion.
To be used immediately after reconstitution.
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Top-selling Gemcitabine injection - Apragem
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Formulations based on "Gemcitabine" (11)
Oncogem 1000 Mg Injection
Gemcitabine
Drug Name Oncogem Composition Gemcitabine Dose/Strength 1000mg Form Injection Manufactured By Cipla Ltd Storage Store below 30°C
Cytogem 1000mg Injection
Gemcitabine
Drug Name CYTOGEM Composition Gemcitabine Dose/Strength 1000mg Form Injection Manufactured By Dr Reddy’s Laboratories Ltd Storage Store below 30°C
Gemchem 1000mg Injection
Gemcitabine
Product Name GEMCHEM Composition Gemcitabine Dose/Strength 1000mg Form Injection Manufactured By Neon Laboratories Ltd Storage Store below 30°C
Amgicin 1000mg Injection
Gemcitabine
Drug Name AMGICIN Composition Gemcitabine Dose/Strength 1000mg Form Injection Manufactured By Adley Formulations Storage Store below 30°C
Gemitrate 1000mg Injection
Gemcitabine
Product Name GEMITRATE Composition Gemcitabine Dose/Strength 1000mg Form Injection Manufactured By Torrent Pharmaceuticals Ltd Storage Store below 30°C
Sibagem 1gm Injection
Gemcitabine
Drug Name SIBAGEM Composition Gemcitabine Dose/Strength 1000mg Form Injection Manufactured By Siba Lifesciences Storage Store below 30°C
Gemget 1000mg Injection
Gemcitabine
Product Name GEMGET Composition Gemcitabine Dose/Strength 1000mg Form Injection Manufactured By GLS Pharma Ltd. Storage Store below 30°C
Gemres 1000mg Injection
Gemcitabine
Product Name GEMRES Composition Gemcitabine Dose/Strength 1000mg Form Injection Manufactured By Resonance Laboratories Pvt Ltd Storage Store below 30°C
Gemcitapar 1000mg Injection
Gemcitabine
Product Name GEMCITAPAR Composition Gemcitabine Dose/Strength 1000mg Form Injection Manufactured By Parenteral Drugs India Ltd Storage Store below 30°C
Apragem 1000mg Injection
Gemcitabine
Drug Name APRAGEM Composition Gemcitabine Dose/Strength 1000mg Form Injection Manufactured By Aprazer Healthcare Pvt Ltd. Storage Store below 30°C
Celzar 1000mg Injection
Gemcitabine
Product Name CELZAR Composition Gemcitabine Dose/Strength 1000mg Form Injection Manufactured By Celon Laboratories Ltd Storage Store below 30°C