Palbociclib
Palbociclib-125
Composition: Palbociclib – 125
Therapeutic Class: Anti-neoplastic
Palbocib: Globally Validated for Efficacy and Safety
Palbocib is widely prescribed by oncologists and is available worldwide.
Aprazer Healthcare: A Global Pharmaceutical Name
Aprazer, a leading pharmaceutical company manufacturing a range of life-saving medicines in varied therapeutic segments. As the largest oncology medicine exporter, it exports anticancer medicines to 50+ countries. WHO-GMP certified, assured therapeutic efficacy and safety.
What is Palbocib?
It is a targeted therapy drug that is used for:
- Hormone-positive (HR+) breast cancer
- HER2-negative and advanced-stage breast cancer
- It targets genetic mutations of the enzymes like HER2, CDK
Uses of Palbocib
- HR+ cancer – hormone receptor-positive breast cancer
- HER2-negative breast cancer
- Metastatic Breast Cancer
How does it work?
Tyrosine Kinase Inhibitor It inhibits the crucial enzymes and arrests the stage of the cell cycle, inhibiting cell proliferation.
- Stops multiplication
- Stops tumor growth
Common Side Effects
- Low blood count – low neutrophils, low RBC count
- Loss of appetite
- Nausea, vomiting
- Mouth ulcers
- Tiredness
- Skin rashes
- Hair loss
Serious Side Effects
- Severe fall in Neutrophils
- Fatal lung inflammation – Pneumonitis
- QT prolongation
- Elevated liver enzymes
- Opportunistic infections – fungal, bacterial
Precautions
To be used cautiously in patients with:
- Pre-existing lung disease
- Liver dysfunctions
- Renal dysfunctions
- Blood disorders
- Cardiac abnormalities
Contraindication
- Not to be used if any previous allergy or hypersensitivity to Palbociclib or any excipients
- Breastfeeding mothers
- Pregnant women
Warning
To be used under medical prescription only.
Important Safety and Monitoring Information
Regular monitoring of the:
- Liver function – Elevated liver enzymes
- Blood count – CBC count
- Respiratory functions – interstitial lung disease
- Cardiac functions – QT prolongation
- Opportunistic infections – fungal, bacterial
Formulations based on "Palbociclib" (11)
Pabreca 125mg
Palbociclib (125mg)
Product Name Pabreca 125mg Composition Palbociclib (125mg) Dose/Strength 125 mg Form Tablet Manufactured By Lupin Ltd Packaging Size 21 capsules in 1 box Prescription Required Storage Store below 30°C
Palbace 125mg
Palbociclib (125mg)
Product Name Palbace 125mg Composition Palbociclib (125mg) Dose/Strength 125 mg Form Tablet Manufactured By Pfizer Ltd Packaging Size 21 capsules in 1 bottle Prescription Required Storage Store below 30°C
Palbinas 125mg
Palbociclib (125mg)
Product Name Palbinas 125mg Composition Palbociclib (125mg) Dose/Strength 125 mg Form Tablet Manufactured By Glenmark Pharmaceuticals Ltd Packaging Size 21 capsules in 1 bottle Prescription Required Storage Store below 30°C
Palbomed 125mg
Palbociclib (125mg)
Product Name Palbomed 125mg Composition Palbociclib (125mg) Dose/Strength 125 mg Form Tablet Manufactured By Medicamen Biotech Ltd Packaging Size 21 capsules in 1 bottle Prescription Required Storage Store below 30°C
Palborest 125mg
Palbociclib (125mg)
Product Name Palborest 125mg Composition Palbociclib (125mg) Dose/Strength 125 mg Form Tablet Manufactured By MSN Laboratories Packaging Size 21 tablets in 1 box Prescription Required Storage Store below 30°C
Paleno 125mg Capsule
Palbociclib (125mg)
Product Name Paleno 125mg Composition Palbociclib (125mg) Dose/Strength 125 mg Form Capsule Manufactured By Sun Pharmaceutical Industries Ltd Packaging Size 21 capsules in 1 bottle Prescription Required Storage Store below 30°C
Piclib Capsule
Palbociclib (125mg)
Product Name Piclib Capsule Composition Palbociclib (125mg) Dose/Strength 125 mg Form Capsule Manufactured By Hetero Healthcare Limited Packaging Size 21 capsules in 1 bottle Prescription Required Storage Store below 30°C
Primcyv 125mg Capsule
Palbociclib (125mg)
Product Name Primcyv 125mg Capsule Composition Palbociclib (125mg) Dose/Strength 125 mg Form Capsule Manufactured By Dr Reddy’s Laboratories Ltd Packaging Size 21 capsules in 1 bottle Prescription Required Storage Store below 30°C
Bdpalbo 125mg Capsule
Palbociclib (125mg)
Product Name Bdpalbo 125mg Capsule Composition Palbociclib (125mg) Dose/Strength 125 mg Form Capsule Manufactured By BDR Pharmaceuticals Packaging Size 21 capsules in 1 bottle Prescription Required Storage Store below 30°C
Palbocib-125
Palbociclib (125mg)
Product Name Palbocib-125 Composition Palbociclib (125mg) Dose/Strength 125 mg Form Tablet Manufactured By APRAZER HEALTHCARE Pvt Ltd Packaging Size 21 capsules in 1 bottle Prescription Required Storage Store below 30°C
Kixta 125mg Capsule
Palbociclib (125mg)
Product Name Kixta 125mg Capsule Composition Palbociclib (125mg) Dose/Strength 125 mg Form Capsule Manufactured By Zydus Healthcare Limited Packaging Size 21 Capsules in 1 box Prescription Required Storage Store below 30°C