Sirolimus
Classification: Organ Transplant Medicine
What is Sirolimus?
It suppresses the immune system and is widely used for organ transplant to prevent rejection, in various cancers, and in rare diseases.
Uses of Sirolimus
- • Organ transplant
- • A rare lung disease – LAM
- • Coated on coronary stents
- • Cancers (off–label)
Common Side Effects
- • High blood pressure
- • High cholesterol
- • Delayed wound healing
- • Skin rashes
- • Nausea
- • Joint pain
- • Swelling
- • Stomach pain
- • Tremors
Serious Side Effects
- • Lung toxicity
- • Risk of infections
- • Liver toxicity
- • Kidney dysfunctions
- • Low blood count
- • Increased risk of malignancies
- • Proteinuria
- • Skin rashes
Precautions
To be used cautiously in:
- • Liver impairment
- • Kidney disorder
- • Bleeding disorder
- • Elderly
- • Lung diseases
- • Planning surgery
- • Drug interactions
Contraindications
- • Should not be used in pregnant women and breastfeeding mothers.
- • Hypersensitivity or allergy to drug components.
Safety Instructions
- • Maintain contraception during the treatment.
- • Avoid live vaccines (MMR, Varicella) due to a compromised immune system.
- • Increased risk of skin cancer, limit direct sun exposure.
Warnings
To be used under medical prescription.
Important Monitoring Considerations
Monitor for –
- • Total blood count
- • Liver and kidney functions
- • Respiratory functions
- • Immune functions
Drug Interactions
- • Antivirals
- • Antacids
- • Antibiotics
- • And other immune suppressants
Gandhi Medicos – Trusted Partner for Transplant Medicines
Understanding the critical need for lifelong transplant medicines, Gandhi Medicos offers an affordable range of transplant medicines and is the largest exporter, distributor, and supplier worldwide.
Why Choose Gandhi Medicos?
- • Trusted by 25,000+ happy clients
- • Preferred by Doctors, hospitals, and patients across the globe.
- • Global reach – delivers in 50 + countries
- • 100% Authentic, Verified Medicines- We outsource only WHO-GMP-approved medicines.
- • Specialists in Chronic & Critical Therapies- We offer robust solutions for HIV, hepatitis, and transplant care.
