Lamivudine, Tenofovir disoproxil fumarate

Composition –
Lamivudine – 300mg
Tenofovir disoproxil fumarate – 300mg

Classification – HIV medicine

Lamivudine + Tenofovir combination

Lamivudine and tenofovir when used in fixed-dose combination is highly effective against HIV and Hepatitis.

Best-selling HIV medicine – Tudobest LE

Uses of the lamivudine and tenofovir combination

  • • HIV-1 infection
  • • Chronic Hepatitis B

Working of Lamivudine and Tenofovir

  • • Both drugs block viral DNA replication and multiplication.
  • • Causes chain termination
  • • Cancer cell death

Benefits

  • • Stronger viral suppression
  • • Improves immunity
  • • Well tolerated
  • • Less frequent dosing
  • • Lowers the chances of resistance
  • • Prevent disease progression and transmission

Common Side Effects

  • • Nausea
  • • Vomiting
  • • Diarrhea
  • • Skin rashes and ulcers
  • • Lightheaded ness

Serious Side Effects

  • • Lactic acidosis
  • • Liver damage – yellowish skin, urine, jaundice
  • • Kidney damage – urine changes, fluid retention
  • • Stomach pain – inflammation in the pancreas
  • • Demineralization of bone – fractures, weakness, pain
  • • Severe allergic reaction – breathing difficulty, rash, swelling

Precautions

To be used cautiously in –

  • • Reduced renal functions – kidney disorders
  • • Liver disorder
  • • Osteoporosis
  • • Elderly
  • • Pregnant, lactating women
  • • Hepatitis B infections
  • • Metabolic dysfunction

Important Monitoring Instructions

  • • Liver functions
  • • Kidney function
  • • Bone mineral density
  • • Lactic acid levels
  • • Viral load and CD4 count

Contraindications

  • • Severe liver dysfunction
  • • Hypersensitivity to drug components

Warnings

To be used under medical prescription.

Co-infection in Hepatitis B patients may cause serious liver flare-ups.

Drug interactions

  • • Anticonvulsant drugs
  • • Cardiovascular drugs
  • • Antihypertensive
  • • Anti-fungal
  • • Anti-tubercular drugs

Gandhi Medicos – 19 years of leadership in HIV care

Gandhi Medicos delivers HIV medicines worldwide.

  • • 400+ Ethical brands
  • • 500+ generic range
  • • Gandhi Medicos is the leading distributor for HIV fixed-dose combination medicines, supplying to hospitals, HIV care centers.
  • • Trusted by leading doctors and patients
  • • 25000+ customers
  • • 3000+ monthly deliveries

Why Gandhi Medicos?

  • • WHO-GMP certified products
  • • Global delivery to 50+ countries
  • • Temperature control shipment
  • • Timely response
  • • Timely delivery

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