Tudobest LE

Composition:

Tenofovir- 300mg

Efavirenz -600mg

Lamivudine -300mg

Classification: HIV medicine

What is Tudobest LE?

A potent drug combination is used once a day for the treatment of HIV infection.

Uses of Tudobest LE

HIV infection

Prophylaxis of HIV

How does it work?

Inhibit viral DNA replication and multiplication, causing cell death.

Benefits

Potent viral suppression

Improves immunity

Well tolerated

Less frequent dosing

Lowers the chances of resistance

Prevent disease progression and transmission

Common side effects

Nausea

Vomiting

Diarrhea

Skin rashes and ulcers

Dizziness

Serious side effects

Lactic acidosis

Yellowish skin, urine, jaundice

Urine changes,

Fluid retention,

Swelling in the legs

Inflammation in the pancreas

Bone fractures, weakness, and pain in bones

Severe allergic reaction - breathing difficulty, rash, swelling

Precautions

To be used cautiously in -

Reduced renal functions-kidney disorders.

Liver disorder

Osteoporosis

Elderly

Pregnant,

Lactating women

Hepatitis B Co-infections

Diabetes,

Obesity

Important monitoring instructions

Liver functions - HBV flare-ups

Kidney function - creatinine levels

Bone mineral density

Lactic acid levels in blood

Viral load and CD4 count

Lipid profile and glucose levels

Contraindications

Severe liver dysfunction.

Hypersensitivity or allergic reaction to the drug or its excipients.

Warnings

To be used under medical prescription.

Do not stop medication immediately - it may cause a Hepatitis B flare-up

Drug interactions

Anticonvulsant drugs

Cardiovascular drugs

Antihypertensive

Anti-fungal and

Anti-tubercular drugs

Tudobest-LE