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Indenza 160 mg (Enzalutamide) is an androgen receptor (AR) inhibitor indicated for patients suffering from prostate cancer types such as,
- Metastatic castration-resistant prostate cancer where other chemotherapy options (docetaxel) did not work. (cancer that lowers the growth of testosterone, a male hormone)
- Metastatic castration-sensitive prostate cancer where other hormonal therapy did not work (cancer that spreads to other parts of the body)
Peculiar properties of Indenza 160 mg (Enzalutamide) that helps in slowing down the growth of prostate cancer,
- Obstructs the communication tool of cancer cells (AR signaling i.e. binding with androgen receptor and interaction with DNA)
- Hinders the unwanted growth (Cell proliferation) of androgen (testosterone)
- Induces the act of self-destruction of cells (Apoptosis)
- Reduces the risk of progression and death
- Postpones the requirement of chemotherapy
When should Indenza 160 mg (Enzalutamide) be avoided or used cautiously?
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- If patients have a history of or experience sudden unwarranted changes in behaviour caused due to disturbances in the brain (Seizures)
- If patients are confirmed with symptoms like headache, impaired vision and low blood pressure (Posterior reversible encephalopathy syndrome)
- If patients are seen with kidney diseases (severe renal impairment and end-stage renal disease)
- If patients show signs of severe disease of the liver
- If patients are seen with a relative risk of heart diseases
- If patients are allergic to dosage and show symptoms like tongue, lip, or pharyngeal swelling (edema)
- If patients are intolerant to lactose
Side-effects of Indenza 160 mg (Enzalutamide):
Most common side-effects:
- Tiredness (Fatigue)
- Pain in the back, muscles, bones and joints
- Diarrhea
- Weakness in the muscles
- Dizziness
- Swelling (edema) in the hands and legs
- Severe headache
- Cold-like symptoms
- Anxiety or stress
Other side-effects:
- Discoloured urine in pink or red colour (Hematuria)
- Rashes on skin
- Trouble in falling asleep (insomnia)
- Trouble in breathing (pneumonia)
- Weakness in the legs
- Pain in the lower back
- High blood pressure (Hypertension)
- Burning or numbness of skin (paresthesia)
- Excitement or confusion
- Loss of memory
- Nightmares
Note:
- These are not all possible side-effects of Indenza 160 mg (Enzalutamide), please ask your doctor for more information regarding the same.
- We are also exporting to countries: Malaysia, Indonesia, Philippines, Venezuela and Korea.
FAQs for Indenza (Enzalutamide 160 Mg)
Drinking alcohol is not recommended while consuming this medicine as it increases the severity of side effects, particularly seizures. Apart from seizures, alcohol can also worsen the overall health of the patient.
It is important to stop the consumption of enzalutamide if swelling occurs in the tongue, face, lips, or throat. Inform your physician and seek medical assistance immediately.
Enzalutamide is an androgen receptor inhibitor that is used in the treatment of prostate cancer in men. This medicine is specifically used when cancer has spread to other parts of the body and cannot be treated with surgery or hormonal therapy.
There is no harm in taking vitamin tablets with enzalutamide. But to avoid health complications, it is always recommended to consult your doctor for information regarding this.
Enzalutamide belongs to a class called androgen receptor inhibitors. These medications help to decrease the androgen hormone and prevent the spread of cancer cells in the body.
A regular dose of enzalutamide helps to slow down the spread of cancer cells in the body. This medicine also prevents the growth of androgen and facilitates the destruction of cancer cells, thus helping treat cancer.
Some of the most common side effects while taking this medication include
- Fatigue
- Headache
- Cold
- Stress
- Anxiety
- Diarrhea
- Weak muscles
Inform your physician in case of severe symptoms.
Enzalutamide can be consumed orally with or without food. The general dosage is once per 24 hours. The strength of the dose to be consumed should be as prescribed by the doctor.
Enzalutamide is available in both Tablet and tablet form. The strength of the Tablet is 160mg only. Tablets are available in 2 different strengths: 160mg and 80mg. Doctors prescribe the most suitable form and strength of this medication based on the health of the patient.
Enzalutamide is also known by the names Indenza and XTANDI. XTANDI is the brand name of this medicine.
Enzalutamide is used only for the treatment of cancer in males. There is still no evidence to support whether this medication is safe for women and children.
Although this medication is used in the treatment of cancer, it is not a chemotherapy drug. Instead, it is a hormone therapy drug used in the treatment of prostate cancer in men.
The less common side effects of enzalutamide include
- Skin rashes
- Discolouration of urine
- Hypertension
- Pneumonia
- Muscle aches
- Paraesthesia
Enzalutamide is a generic medicine but is often referred to by its brand name XTANDI.
It is important to take the following precautions while taking this medication:
- Inform your doctor about your previous medical history
- Inform your doctor about other drugs and medicines that you are consuming.
- Any kind of vaccination should be avoided without the doctor’s permission.
- Be sure to discuss your allergies with your doctor.
- In case of severe side effects, seek medical help at the earliest.
It is suggested not to go for driving or any other related activities until the patient is sure about the side effects of the medicine. Consult your healthcare provider for advice.
Ibuprofen might increase the risk of internal bleeding in the case of heart patients. Instead, acetaminophen tablets are safe for consumption. However, always discuss with your doctor for a suitable dosage.
Enzalutamide has an impact on the brain and can result in severe depression and changes in cognitive function. However, this is not very common for all patients.
There might be symptoms of liver damage, but it is not very serious and can be cured with proper medication.
Yes, patients do lose taste and smell. Favorite food and other liquids will seem to be tasteless. This can last longer for several weeks and months.
The following measures can be taken to stay healthy:
- Take plenty of rest and highly nutritious food
- Do not take any other medicines without the approval of your doctor.
- Avoid drinking alcohol.
- Avoid indulging in activities that might cause injuries.
- Keep your hands clean.
- Keep your doctor informed about your health condition regularly.
While considering the treatment of prostate cancer, both Zytiga and enzalutamide are used. But enzalutamide is considered to be more effective in treatment as recorded by a medical study.
Patients consuming enzalutamide may develop a health issue related to the brain called PRES. Other symptoms include headache, confusion, reduced alertness, loss of eyesight, etc. Consult your healthcare provider for medical aid.
Enzalutamide does not have severe effects on the kidney. But some patients experienced some issues related to the urinary tract. If such issues occur, medication can help to cure kidney diseases.
If prescribed to take regular doses of enzalutamide, it is not recommended to skip the doses or remain inconsistent with the consumption of enzalutamide. If so, the treatment of prostate cancer slows down and can result in the overall deterioration in the health of the patient.
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