Abirakast (Abiraterone acetate) is a recently discovered hormonal therapy for adult male patients suffering from prostate cancer. Abirakast 250 mg (Abiraterone acetate) is an oral drug which inhibits the action of proteins (CYP17A1 enzyme) that are responsible for producing a male hormone called testosterone. Abiraterone acetate targets the excessive production of testosterone as prostate cancer cells require these hormones to flourish. Abiraterone acetate is specifically used in patients with prostate cancer,
- Where other chemotherapy options (docetaxel) did not work (metastatic castration-resistant prostate cancer)
- In adults with mild symptoms or no symptoms where chemotherapy has not been given yet or other hormonal therapies (androgen deprivation therapy) do not work
Peculiar advantages of Abirakast 250 mg (Abiraterone acetate):
- It keeps prostate cancer under control
- Increases duration of life-span
- Delays or rectifies common symptoms such as pain and tiredness
Abiraterone acetate is used in combination with prednisone (a drug used to suppress the immune system for reducing inflammation). When used together, abiraterone acetate impart advantages such as,
- Reduction of hypertension as a side-effect
- Lowering the production of antigen that stimulates prostate cancer
- Induction of hunger for a stable diet
Administration of Abirakast 250 mg (Abiraterone acetate):
Abiraterone acetate is given orally in 1000 mg concentrations i.e. 4 tablets of 250 mg once a day. Along with abiraterone, prednisone 5 mg is also given twice daily. Once administered, abiraterone acetate gets readily-absorbed (bioavailable) within 2 hours throughout the body. Once abiraterone acetate completes its action, approximately 55% of the drug is expelled from the body in between 5-14 hours. Abiraterone acetate is recommended on an empty stomach. Consumption of food should be completely avoided for at least 2 hours prior and 1 hour after the dose. Avoid crushing or swallowing tablets without water. It is equally important to avoid grapefruit juice as it triggers unwanted side-effects.
When should Abirakast 250 mg (Abiraterone acetate) be avoided or used cautiously?
- If patients were previously suffering from heart diseases or failure
- If patients have hypertension or arrhythmia, carry out blood tests monthly
- In patients have stress, steroid hormones used for retention of water and production of potassium are not produced (adrenocortical insufficiency), in that case, corticosteroid drugs (prednisone) are recommended
- If patients have complications of the liver causing an increase in the production of unwanted liver proteins (hepatoxicity)
Most common side-effects of (abiraterone acetate):
- Unwanted swelling (edema)
- Tiredness
- Discomfort in joints and muscles
- Problems in the stomach like diarrhea, indigestion and vomiting
- Shortness of breath (dyspnea) or infection in the upper respiratory tract
- Feeling uncomfortably hot (Hot flush)
- Cough
- Urinary tract infection
Laboratory side-effects of (abiraterone acetate):
- Low levels of potassium (hypokalemia) and phosphate (hypophosphatemia)
- Weakness caused due to lack of hemoglobin in the blood (anemia)
- High levels of fat molecules (triglycerides) (hypertriglyceridemia), cholesterol (hypercholesterolemia), and sugars (hyperglycemia)
Augmented levels of proteins/enzymes like aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase
Note: We are also exporting to countries: Malaysia, Indonesia, Philippines, Venezuela and Korea.
FAQs for Abirakast
Abirakast is prescribed against advanced prostate cancer.
Abiraterone Acetate is the active ingredient in Abirakast.
Abirakast 250 mg are manufactured by BDR Pharmaceuticals Pvt Ltd. and branded by Aprazer Healthcare Pvt Ltd.
Yes, It has to be consumed only with a proper doctor’s prescription.
The Abiraterone Acetate in Abirakast reduces the production of androgen, which promotes the growth of tumors in the body. It is recommended for patients whose prostate cancer cannot be treated through surgical or other pharmaceutical interventions.
Abiraterone Acetate in Abirakast checks prostate cancer progression increases life span and delays common symptoms like tiredness and pain.
It is prescribed to be used with prednisone or prednisolone. This depends on the cancer treatment received by the patients.
It is used in combination with prednisone for patients with prostate cancer who are resistant to metastatic castration and have received docetaxel-containing chemotherapy treatment.
A combination of prednisone or prednisolone and Abirakast is prescribed for adult men with prostate cancer resistant to metastatic castration but are mildly symptomatic or asymptomatic after androgen deprivation therapy has failed and for whom clinical chemotherapy has not been prescribed.
When used with prednisone, Abirakast reduces hypertension as a possible side-effect and reduces antigens’ production that stimulates prostate cancer.
It must be administered orally daily in 1000mg dosages on four tablets of 250 mg and be taken on an empty stomach. This means the Abirakast administration has to be done with an empty stomach, either two hours after meals or one hour before meals. 10mg prednisone will be administered along with Abirakast tablets, and the drug has to be taken at the same time daily.
The most likely side-effects of consuming Abirakast include unwanted swelling, muscular and joint discomfort, and stomach problems like vomiting, diarrhea, and indigestion. It may cause other side effects like shortness of breath or upper respiratory tract infection, enduring hot flush or feeling uncomfortably hot, and illness in the urinary tract.
Patients may rarely have irregular heartbeats, cannot urinate for over eight hours, have difficulty breathing, or a fever of 100.4°F with chills. If patients exhibit any of these symptoms after intaking this tablet, medical assistance must be sought at the earliest.
Suppose the patient has a severe headache, dizziness, extreme fatigue, unusual spike in blood pressure, yellowing of skin and eyes, blood in stools, diarrhea, or unusual bleeding. In that case, medical assistance has to be sought, though they are not life-threatening.
Patients who had heart conditions or liver complications that can cause hepatoxicity or increased production of unwanted liver proteins should be cautious and seek the doctor’s help before consuming it.
Patients should get their blood tested every month if they suffer from hypertension or arrhythmia while intaking this tablet. They should take corticosteroid drugs like prednisone, which is used in combination with Abirakast if they suffer from stress or due to the non-production of water-retaining and potassium-producing steroids.
The recommended daily dosage of Abirakast is 1000 mg or four tablets with a dosage of 250mg.
No side effects were found during clinical studies of Abirakast overdosage. However, patients who had an overdosage of it should undertake general supportive measures like monitoring for heart and liver failure.
Laboratory side-effects of this tablet intake include low levels of potassium and phosphorous, weakness due to amnesia or the lack of hemoglobin in the blood, and high levels of cholesterol, fat molecules, and sugars.
It cannot be prescribed for children.
It can be prescribed for pregnant women. However, they should stay away from the drug during pregnancy. Suppose the patient is using the medicine during pregnancy or becomes pregnant during the course. In that case, she should be made aware of the drug’s potential risks.
Nursing women are advised to avoid the drug as there are high potentials of severe reactions of Abirakast in nursing children.
Patients with mild hepatic impairment and renal impairment do not require any dose adjustment. However, patients with moderate hepatic impairment should restrict the daily dosage to one tablet. The drug has to be avoided entirely by patients with severe hepatic impairment.
Yes, It is safe for geriatric use.
The tablets should be ideally stored at room temperature and should not be exposed to heat or light. However, the tablets should not be stored in a freezer.
A packet of Abirakast tablets has a shelf life of three years. However, customers must check out the expiration date on the back of the cover. The expiration date is the last day of the month mentioned, and customers should not use the tablets beyond that date.
These tablets are packed in an HDPE container containing 120 tablets. These containers are packed in a mono carton and a pack insert.
It can be purchased directly from the manufacturers without the need for intermediaries. The suppliers follow strict regulations during the procurement of the drug. Only “fresh-batch” consignments are supplied.
William (verified owner) –
Your website is user-friendly. They always response quickly.
Camden (verified owner) –
Excellent experience with Gandhi Medicos Genuine life-saving medicines. The packaging was a safe, trusted source for critical medications
Hayden (verified owner) –
I rely on Gandhi Medicos for my essential medicines, and they’ve never let me down. Their support and efficient service are much appreciated
George Simmons –
Abirakast is the best medicine for the treatment of advanced prostate cancer.
Craig Heywood –
My doctor recommended that I take Abirakast. Abirakast is, in my opinion, one of the best medicine for the treatment of prostate cancer.
Shubham Bhatnagar –
Abirakast is a well-known medicine for treating prostate cancer.
Patrick (verified owner) –
I’m so glad I found Gandhi Medicos. They’ve been a reliable source for my medicines, always delivered on time and with great packaging. Highly recommended for original medicines.
Edward (verified owner) –
We got delivery of medicines from Gandhi Medicos on time, we feel relieved!
Jackson (verified owner) –
Excellent experience with Gandhi Medicos Genuine life-saving medicines. The packaging was a safe, trusted source for critical medications
Nathaniel (verified owner) –
Value for Money and genuine products received from Gandhi Medicos.
John (verified owner) –
I rely on Gandhi Medicos for my essential medicines, and they’ve never let me down. Their support and efficient service are much appreciated
Dominic (verified owner) –
I am a loyal customer of Gandhi Medicos since last 5 years. Thank you!
Alan (verified owner) –
Excellent!!! always exceeding our expectations.
Patrick (verified owner) –
Ordered medication from Gandhi Medicos and received it within hours! Talk about efficiency!
Owen (verified owner) –
I rely on Gandhi Medicos for my essential medicines, and they’ve never let me down. Their support and efficient service are much appreciated