MyHep All Tablet Uses Benefits and Side Effects
MyHep All (sofosbuvir 400mg + velpatasvir 100mg) is a fixed-dose combination (FDC) drug recommended against chronic hepatitis C viral (HCV) infection in adults. MyHep All (sofosbuvir 400mg + velpatasvir 100mg) is indicated for patients suffering from HCV genotype 1 to 6.
MyHep All (sofosbuvir 400 mg + velpatasvir 100 mg) is regarded as one of the most potent anti-HCV agents attaining 93-99% sustained virologic response (SVR) after 12 weeks of therapy based on genotype and the levels of cirrhosis.
What is Chronic Hepatitis C
Chronic hepatitis C is a persistent viral infection affecting the liver. Chronic hepatitis C is primarily transmitted through blood contact, such as sharing needles or receiving tainted blood transfusions. Over time, it can lead to liver damage, cirrhosis, and even liver cancer. Symptoms may be mild or absent initially, but can progress to fatigue, jaundice, and abdominal pain. Treatments are available to manage the infection and prevent complications.
FDC combination (sofosbuvir + velpatasvir) imparts advantages such as,
- Treatment of almost all genotypes (1-6) of HCV infection
- More than 90% of SVR in HCV patients with scarring of the liver (cirrhosis) in all genotypes
The FDC combination belongs to the class of direct-acting antiviral (DAA) drugs which explicitly inhibits a specific type of protein (RNA polymerase) that stops the multiplication (RNA replication) of cells reducing the viral load.
Administration of MyHep All (sofosbuvir 400mg + velpatasvir 100mg):
The drug is administered in a form a fixed-dose combination i.e. 1 tablet (sofosbuvir + velpatasvir combination) once daily. It can be taken with or without food.
Suggested dosage of MyHep All (sofosbuvir 400mg + velpatasvir 100mg) in patients with genotypes 1 to 6 HCV:
HCV disease type | Dosage | Duration (weeks) |
No cirrhosis and cirrhosis with a functional system | MyHep All (sofosbuvir + velpatasvir) (1 tablet) | 12 |
Cirrhosis with an unfunctional system | MyHep All (sofosbuvir + velpatasvir) plus ribavirin | 12 |
Other properties of the FDC combination drug:
Properties | Sofosbuvir | Velpatasvir |
Inhibited protein | Non-structural protein 5B (NS5B) | Non-structural protein 5A (NS5A) |
Absorption in the system (Bio-availability | 30 minutes to 2 hours | 3 hours |
Binding affinity with viral cells | 61 to 65% | 99% |
Excretion time | 40 minutes to 27 hours for 50% drug molecule | 15 hours for 50% drug molecule |
Note: The duration and frequency of dosage can be changed based on the initial experience of the patients. It is mostly dependent on the doctor’s judgement
When should Hepcvel (sofosbuvir 400mg + velpatasvir 100mg) be avoided or used cautiously?
- If patients are suffering from or had a history of Hepatitis B viral infection before taking sofosbuvir.
- If patients are suffering from kidney disease or undergoing dialysis or other severe medical condition
- If patients had a liver transplant before the initiation of dosage
- If patients have complications in the liver other than HCV infection
- If patients are pregnant and planning to breastfeed
Side-effects of Hepcvel (sofosbuvir 400mg + velpatasvir 100mg)
Most common side-effects:
- Headache
- Tiredness (Fatigue)
Serious side-effects: Slow heart rate (bradycardia)
Side-effects in HCV patients without cirrhosis or cirrhosis with a functional system:
- Physical weakness (Asthenia)
- Lack of sleep (Insomnia)
- Nausea
- Headache
- Tiredness
Side-effects in HCV patients with cirrhosis and an unfunctional system:
- Low count of red blood cells (RBCs) (Anemia)
- Lack of sleep
- Headache
- Diarrhea
- Nausea
- Tiredness
Uncommon side-effects:
- Depression
- Severe rashes on the skin
Note:
- These are not all possible side-effects of Hepcvel (sofosbuvir 400mg + velpatasvir 100mg), please ask your doctor for more information regarding the same.
- We are also exporting to countries: South East Asia, South America, USA (California, Las Vegas, San Francisco), Eastern Europe (Bulgaria, Croatia, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Macedonia, Poland, Republic of Kosovo, Republic of Moldova, Romania, Russia, Serbia, Slovak Republic, Slovenia, Malaysia, Indonesia, Philippines, Venezuela and Korea.) and many more…
Maya Joseph –
MyHep All is the best medicine for the treatment of chronic hepatitis C viral (HCV) infection in adults.
Mark Jordan –
I am taking myhep all from last three months. It is very effective medicine againts hepatitis C.
Russell Foulger –
Very effective medicine for HCV genotype 1 to 6.
Adan –
My experience with Gandhi Medicos was fantastic! Their prompt delivery and affordable prices for MyHep All exceeded my expectations.
Rajesh –
I received MyHep All on time and at a great price.
Rashid –
Thank you for the great service!
Ethan –
Thanks a lot, Gandhi Medicos, for the swift delivery and affordable prices for MyHep All.
Rachel Thompson –
Gandhi Medicos’ quick delivery and budget-friendly prices
Sophia –
Excellent service from Gandhi Medicos! MyHep All was delivered quickly, and the prices were very competitive. Thanks a lot for the great deal !