Sovihep

SoviHep 400 mg (Sofosbuvir) is a renowned anti-Hepatitis C viral (HCV) drug used in combination with other agents like ribavirin or peginterferon. SoviHep 400 mg (sofosbuvir) operates by reducing the amount of HCV cells in the body. Besides, it also assists in decreasing the incidence of liver complications like cirrhosis (scarring of the liver) and liver cancer. The dosage of SoviHep 400 mg (Sofosbuvir) differs based on the genotype of HCV and duration of treatment. Preferably, 400 mg tablet once daily is recommended irrespective of food.

In patients with genotype 1 or 4, SoviHep 400 mg (Sofosbuvir) is combined with ribavirin and peginterferon alfa for 12 weeks. Whereas, in genotype 2, the same combination is given without peginterferon alfa. In genotype 3, the duration of the dosage is extended from 12 to 24 weeks with the same combination as genotype 2.

In conditions (genotype 1) where peginterferon alfa cannot be used, SoviHep 400 mg (Sofosbuvir) plus ribavirin are given for 24 weeks instead of 12 weeks. Whereas, in liver cancer patients waiting for their transplant operation, the same combination can be used for 48 weeks or until the time of liver transplantation.

General instructions for patients:

Before taking (Sofosbuvir),

• Inform the doctor about diabetes, kidney disease or dialysis, or liver disease
• Discuss allergies that may be related to SoviHep 400 mg (Sofosbuvir), food, and current medicines
• Inform your doctor if you are undergoing liver transplant surgery
• Mention about any history related to HIV infection
• Discuss pregnancy-related and breastfeeding issues

While taking (Sofosbuvir),

• It is important to carry out regular blood tests
• Use contraceptives methods to avoid pregnancy

Side-effects of SoviHep 400 mg (Sofosbuvir):

SoviHep 400 mg (Sofosbuvir) has one of the most favourable safety and tolerability profile among other anti-HCV agents. It shows only two common side-effects including tiredness and headache. These side-effects can be easily dealt with. If peginterferon alfa and ribavirin are used especially in genotype 1 patients, nausea, difficulty in sleeping, and low count red blood cells are seen along with the other two common side-effects.

Note: The aforementioned side-effects may not be the only ones for SoviHep 400 mg (Sofosbuvir). Consult your doctor for more information.

Warnings and precautions related to SoviHep 400 mg (Sofosbuvir):

The advent of Bradycardia due to amiodarone administration:

There are chances of serious adverse events if patients are taking amiodarone along with SoviHep 400 mg (Sofosbuvir). It is very crucial to avoid them taking together. If taken, it is necessary that patients undergo continuous cardiac monitoring and consulted immediately if they are seen with symptoms like chest pain, confusion, dizziness, and shortness of breath.