Apremilast
Classification: Rheumatology Medicine
What is Apremilast?
Rheumatology care treatment is used for arthritis and various other autoimmune conditions.
Uses of Apremilast
- • Psoriatic arthritis
- • Plague psoriasis
- • Mouth ulcers
How Does Apremilast Work?
- • It blocks PDE4 enzyme activity.
- • It calms down inflammation and an overactive immune system.
Benefits
- • Heals painful ulcers
- • Reduces joint pain and swelling
- • Heals skin symptoms
- • Eliminates need for injections
- • Lesser risk of immune suppression
Common Side Effects
- • Nausea
- • GIT upset
- • Reduced appetite
- • Nasal congestion or runny nose
- • Headache
- • Weakness
- • Pain in the back
Serious Side Effects
- • Severe dehydration
- • Neurological dysfunctions – mood swings, depression
- • Loss of appetite and weight loss
Precautions
To be cautiously used in –
- • Neurological condition – depression, any mood swing
- • Kidney disorders
- • Severe diarrhea
- • Underweight
- • Pregnant or breastfeeding women
Contraindications
Not to be used in patients-
- • Hypersensitivity or allergy to the drug composition.
- • Severe kidney impairment
- • Pregnant and breastfeeding
Warnings
Prescription drug to be used under medical supervision.
Important Safety and Monitoring Information
- • Kidney function tests
- • Weight measurement
- • Neurological condition: mood swings
- • Gastrointestinal functions
- • Blood count and other hematological functions
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